【摘要】 越来越多的证据表明,肠道菌群结构紊乱与心血管疾病的发生密切相关。氧化三甲胺作为肠道菌群的代谢产物,在心血管疾病的发生和发展中起重要作用。现就氧化三甲胺与冠心病、心力衰竭、高血压、心房颤动和心肌纤维化的关系及其可能的机制做一综述,为心血管疾病的防治提供新靶点。更多还原

【Abstract】 More and more evidences show that intestinal flora disorders are closely related to the occurrence of cardiovascular diseases. Trimethylamine oxide, as the metabolite of intestinal flora,plays an important role in the occurrence and development of cardiovascular diseases. This article reviews the relationship between trimethylamine oxide and coronary heart disease,heart failure,hypertension,atrial fibrillation and myocardial fibrosis,and its possible mechanism,so as to provide a new target for the prevention and treatment of cardiovascular diseases.更多还原