【摘要】 背景:研究认为,富血小板血浆可以促进组织的修复和再生。目的:通过文献计量学的方法评价全球富血小板血浆领域的研究现状和热点。方法:在web of science核心库中,采用普通检索的方式,以"platelet rich plasma"等为关键词进行主题检索,分析从建库至2018-12-25发表的相关研究。通过对已检索的文献按照国家地区、机构、出版年、来源出版物名称等分别进行索引和分析。使用Excel 2007进行描述性统计。使用VOS viewer(Leiden University,荷兰)软件对检索的全部条目进行分析并绘制图形。主要评价指标包括:共现关系、互引关系、共引关系以及合作关系图。结果与结论:①共检索到8 499篇富血小板血浆方面的研究,研究数量和被引用次数逐年增加;②富血小板血浆研究数量排名前3名的国家是美国、意大利和日本;③富血小板血浆的学科方向和研究领域主要涉及5方面:生长因子功能的基础研究、骨再生领域研究、软骨或骨关节炎相关领域的临床研究、血小板功能研究以及干细胞相关研究领域;④基于大数据的分析结果提示,富血小板血浆的主要研究和应用领域在骨科,尤其是软骨再生和骨关节炎方面,未来富血小板血浆的研究重心和科技投入应该向其倾斜。更多还原

【Abstract】 BACKGROUND: Platelet-rich plasma has been shown to promote tissue repair and regeneration. OBJECTIVE: To evaluate the current status and hotspot of platelet-rich plasma globally by bibliometrics. METHODS: In the database of web of science, "platelet rich plasma" was used as keyword to research relevant researches published before December 25, 2018. The retrieved articles were indexed and analyzed according to country/region, institution, publication year, and publication name. Excel 2007 was used for descriptive statistics. VOS viewer(Leiden University, Netherlands) software was used to analyze and draw all the retrieved items. The main evaluation indicators were co-occurrence relationship, mutual citation relationship, co-citation relationship, and cooperation relationship map. RESULTS AND CONCLUSION:(1) Totally 8 499 studies on platelet-rich plasma were retrieved, and the number and citations increased gradually.(2) Number of studies on platelet-rich plasma ranked top 3 countries are the United States, Italy, and Japan.(3) The subject direction and research fields of platelet-rich plasma mainly involve five aspects: basic research on growth factor function, research on bone regeneration, clinical research in cartilage or osteoarthritis, platelet function research, and stem cells.(4) The analysis results based on big data suggest that platelet-rich plasma is mainly applied in orthopedics, especially cartilage regeneration and osteoarthritis, which will be the focus of future research and technology investment.更多还原