【摘要】 目的观察并探讨采用免疫抑制治疗再生障碍性贫血的临床效果。方法选取某院血液科于2019年3—10月收治的再生障碍性贫血患者64例,随机分为试验组和对照组各32例,试验组采用免疫抑制疗法,对照组采用常规疗法,治疗6个月后,观察比较两组的血象和T淋巴细胞亚群变化及临床治疗效果。结果治疗后,试验组的Hb、PLT、ANC、WBC的指标水平均高于对照组(P <0.05);试验组的CD3+、CD4+及CD4+/CD8+比值高于对照组,CD8+低于对照组(P<0.05);试验组的总有效率高于对照组(P <0.05)。结论采用免疫抑制治疗再生障碍性贫血的临床效果优于常规疗法。更多还原

【Abstract】 Objective To observe and discuss the clinical effect of immunosuppression on aplastic anemia. Methods 64 patients with aplastic anemia admitted from March to October 2019. The experimental group used immunosuppressive therapy and the control group used conventional therapy. After 6 months of treatment, observed the changes of blood and T lymphocyte subsets and clinical treatment effect between the two groups. Results After treatment, the indexes of Hb, PLT, ANC, and WBC in the experimental group were higher(P < 0.05); the CD3+, CD4+, CD4+/CD8+ ratio of the experimental group were higher, the CD8+ ratio of the group was lower(P < 0.05); the total effective rate of the experimental group was higher than that of the control group(P < 0.05). Conclusion The clinical effect of using immunosuppressive therapy to treat aplastic anemia is better than conventional therapies.更多还原