【摘要】 目的了解泰安市麻疹发病及免疫状况,为麻疹的监测与防治工作提供依据。方法采用酶联免疫吸附试验和实时荧光定量PCR技术对麻疹疑似病例进行检测,同时进行回顾性分析。结果 2013—2018年泰安市共报告1 690例麻疹疑似病例,采样率为84. 32%,其中麻疹阳性642例,阳性率为45. 05%,年平均发病率(1/10万)分别为1. 84、0. 88、5. 10、3. 00、0. 32、0. 30,不同年份麻疹发病率之间的差异有统计学意义(χ~2=28. 862,P <0. 01)。麻疹发病具有季节性升高的特征,以3～5月高发;各县市区中阳性病例构成前3位分别为新泰市(25. 70%)、岱岳区(21. 18%)和泰山区(19. 78%); 8月龄～1岁年龄组阳性病例最多,共162例;麻疹确诊病例中23. 21%有免疫史。结论加强监测,提高免疫及其成功率是控制麻疹的关键。更多还原

【Abstract】 Objective: To understand the incidence and immune status of measles in Taian City,and to provide evidence for the monitoring and prevention of measles. Methods: Enzyme-linked immunosorbent assay (ELISA) and Real-Time PCR were used to detect suspected cases of measles,and retrospective analysis was performed. Results: In 2013-2018,a total of 1690 suspected cases of measles were reported in Taian City,with a sampling rate of 84. 32%,of which 642 were positive for measles,the positive rate was 45. 05%,and the annual average incidence rate (1/100 000) was 1. 84,0. 88,5. 10 respectively. 3. 00,0. 32,0. 30,and the difference between the incidence of measles in different years was statistically significant (χ~2= 28. 862,P < 0. 01). Conclusion: Strengthening monitoring and improving immunization and its success rate are the key to controlling measles.更多还原