【摘要】 目的探究个体化饮食指导应用于慢性乙型肝炎(以下简称"慢性乙肝")伴2型糖尿病患者中的效果。方法将2018年3月—2019年3月该院收治的78例慢性乙肝伴2型糖尿病患者作为研究样本,根据双盲法分组标准均分成两组,对照组(n=39)给予常规护理,试验组(n=39)给予个体化饮食指导。比较两组肝功能改善情况与血糖指标。结果护理后,试验组总胆红素正常率51.28%、HBV-DNA转阴率61.54%、丙谷转氨酶正常率71.79%与对照组15.38%、28.21%、33.33%比较,差异有统计学意义(χ~2=11.308,P=0.001;χ~2=8.759,P=0.003;χ~2=11.570,P=0.001);对照组治疗后空腹血糖(8.13±2.59)mmol/L、餐后2 h血糖(9.84±2.25)mmol/L、糖化血红蛋白(7.40±2.03)%与试验组(6.70±2.31)mmol/L、(7.30±1.72)mmol/L、(6.01±0.77)%比较,差异有统计学意义(t=2.573,P<0.05;t=5.601,P<0.05;t=3.998,P<0.05)。结论个体化饮食指导能改善慢性乙肝伴2型糖尿病患者的肝功能,还可调节血糖水平,临床推广价值高。更多还原

【Abstract】 Objective To explore the effect of individualized dietary guidance in patients with chronic hepatitis B(hereinafter referred to as "chronic hepatitis B") and type 2 diabetes. Methods A total of 78 patients with chronic hepatitis B and type 2 diabetes admitted in our hospital from March 2018 to March 2019 were used as research samples. They were divided into two groups according to the double-blind grouping standard, and the control group(n=39) was given routine care and the experimental group(n=39) gave individualized dietary guidance. Compare the improvement of liver function and blood glucose index between the two groups. Results After care, the normal rate of total bilirubin in the test group was51.28%, the HBV-DNA negative rate was 61.54%, and the normal rate of alanine aminotransferase was 71.79%. The difference was statistically significant(15.38%, 28.21%, 33.33%)(χ~2=11.308, P=0.001; χ~2=8.759, P=0.003; χ~2=11.570, P=0.001);fasting blood glucose(8.13±2.59)mmol/L after the treatment in the control group, blood glucose(9.84±2.25)mmoll/L 2 h after meal, glycosylated hemoglobin(7.40±2.03)% compared with the experimental group(6.70±2.31)mmol/L,(7.30±1.72)mmol/L,(6.01±0.77)%, the difference was statistically significant(t=2.573, P<0.05; t=5.601, P<0.05; t=3.998, P<0.05). Conclusion Individualized dietary guidance can improve the liver function of patients with chronic hepatitis B and type 2 diabetes, and it can also regulate blood glucose levels, which has high clinical popularization value.更多还原