【摘要】 目的观察银杏叶片联合多奈哌齐治疗血管性痴呆的临床疗效。方法将110例血管性痴呆患者分为2组,每组55例。对照组给予多奈哌齐治疗;试验组给予银杏叶片联合多奈哌齐治疗。治疗3个月后,比较2组蒙特利尔认知测试(MoCA)评分、日常生活能力量表(ADL)评分及临床疗效。结果①对照组和试验组治疗后MoCA评分比较差异有统计学意义(P<0.05)。②对照组和试验组治疗后ADL评分比较差异有统计学意义(P<0.05)。③试验组总有效率明显高于对照组(P<0.05)。④2组患者在治疗过程中均未见明显不良反应。结论银杏叶片联合多奈哌齐治疗血管性痴呆的临床疗效优于单用多奈哌齐组。更多还原

【Abstract】 Objective To observe the clinical effect of Ginkgo Leaves Tablets combined with Donepezil in the treatment of vascular dementia. Methods One hundred and ten patients with vascular dementia were randomly divided into two groups,55 in each group. The control group was treated with Donepezil,and the experimental group was treated with Ginkgo Leaves Tablets combined with Donepezil. After 3 months of treatment,the Montreal cognitive assessment(MoCA)score,Ability of daily living(ADL)score and clinical efficacy of the two groups were compared. Results ①There was significant difference in MOCA score between the control group and the experimental group(P<0.05). ② There was significant difference in ADL score between the control group and the experimental group(P <0.05). ③ The total effective rate of the experimental group was significantly higher than that of the control group(P<0.05). ④ No significant adverse reactions were found in the two groups. Conclusion The clinical effect of Ginkgo Leaves Tablets combined with Donepezil in the treatment of vascular dementia is better than that of Donepezil alone.更多还原