【摘要】 目的制备黑磷纳米片,并对其降解特性进行评价。方法首先通过优化的液相剥离法制备了黑磷纳米片,并采用马尔文激光粒度仪、透射电镜、紫外可见分光光度计对其粒径、电位、形态及光学性质进行了表征;其次,作为一种生物可降解纳米材料,其降解性对降低体内毒性具有重要意义。因此,针对它的降解特性,考察了不同溶剂及不同pH值对黑磷纳米片降解行为的影响。结果所制备的黑磷纳米片为片层结构,粒径约200 nm且具有较强的近红外吸收。黑磷纳米片在水溶液中较剥离溶剂中降解速率较快,放置8 d后降解率可达73%,在N-甲基吡咯烷酮中放置8 d仅降解10%,在pH值为12的溶液中降解速率最快。结论优选处方制备的黑磷纳米片粒径均匀,光热效应良好;黑磷纳米片在N-甲基吡咯烷酮中降解速率较慢,对于其短期储存提供了适宜的溶剂;在不同pH值溶液中的降解特性具有选择性,对于研究其在生物医药领域中的应用起一定帮助。更多还原

【Abstract】 Objective To prepare black phosphorus and to evaluate the degradation properties.Methods Black phosphorus nanosheets were prepared by modified liquid exfoliation method.The size distribution and Zeta potential of black phosphorus nanosheets were measured using dynamic light scattering(DLS) and its morphology was characterized by transmission electron microscopy(TEM).And the optical property was evaluated by UV-Vis absorption spectrum.In addition,as a biodegradable nanomaterial,its degradability is of great significance in reducing toxicity in vivo.Therefore,the effects of different solvents and pH on its degradation behavior were investigated.Results The results showed that black phosphorus nanosheets displayed uniform 2 D sheet-like morphology with a diameter of about 200 nm and it had strong near-infrared absorption.It was found that the degradation rate of black phosphorus nanosheets in water was faster than that in the stripping solvent.After 8 days,the degradation rate reached 73% in water and the degradation rate was only 10% in NMP.Its degradation rate was fastest in the solution of pH 12.Conclusion Particle size of black phosphorus nanosheets is uniform and it has good photothermal effect.Solvents and pH have an influence on the degradation of black phosphorus nanosheets.The degradation of black phosphorus nanosheets in water is faster than in N-methylpyrrolidone.In the solution of different pH,black phosphorus nanosheets degrades fastest in NaOH solution at pH 12.更多还原