【摘要】 目的探讨基于磁化转移技术的三维时间飞跃法磁共振血管成像技术(3D-MT-TOF-MRA)在颅内血管狭窄诊断中的价值。方法收集2017年6月至2019年8月符合缺血性脑血管疾病患者40例,所有患者均行基于磁化转移技术的3D-MT-TOF-MRA、TOF-MRA及数字减影血管造影(DSA)检查。以DSA、3D-MT-TOFMRA对照,对比分析3D-MT-TOF-MRA判断颅内血管狭窄的敏感度、特异度、准确度。结果所有患者均顺利完成检查,观察期内无不良事件发生。40例患者基于磁化转移技术的3D-MT-TOF-MRA检出中小血管狭窄27例(27/40,68%),DSA检出30例(30/40,75%),3D-MT-TOF-MRA检出血管狭窄20例(20/40,50%),3种方法诊断颅内中小血管狭窄差异有统计学意义(P<0.05)。以DSA为对照,基于磁化转移技术的3D-MT-TOF-MRA检出颅内中小血管狭窄的敏感度为87%,特异度为90%;2种方法诊断颅内中小血管狭窄差异无统计学意义(P>0.05),进一步κ系统检验,两种方法吻合度一般(κ=0.637)。结论 3D-MT-TOF-MRA技术与DSA在判断颅内动脉狭窄上具有较高一致性,且具有经济、安全等优点,值得临床进一步研究。更多还原

【Abstract】 Objective To investigate the application value of 3 D-MT-TOF-MRA technology in the diagnosis of ischemic cerebrovascular diseases. Methods Forty cases of ischemic cerebrovascular diseaseswere invloved in this study, in which all patients were performed routine abdominal TOF-MRA, DSA and 3 D-MT-TOF-MRA. The sensitivity, specificity and accuracy of 3 D-MT-TOF MRA technology in the diagnosis of ischemic cerebrovascular diseaseswere compared and analyzed, on the control of data from 3 D-TOF-MRA, DSA. Results All patients successfully completed the examination, and no adverse events occurred during the observation period.In 40 cases of ischemic cerebrovascular diseases, the 3 D-MT-TOF-MRA detected 27 cases vascular stenosis(27/40,68%), compared to 30 cases in DSA(30/40,75%), 20 cases in 3 D-MT-TOF-MRA(20/40,50%). There were evident statistic significance among three image technology in vascular stenosisdetected(P<0.01). Compared with DSA, the sensitivity of3 D-MT-TOF-MRA was 87%, specificity was 90% and Kappa value was 0.637. Conclusion 3 D-MT-TOF MRA technologyhas high consistency with DSA in the diagnosis of ischemic cerebrovascular diseases, with merits of safety and economy,which deserves further clinical research.更多还原