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射血分数保留型心力衰竭合并2型糖尿病病人的临床及冠状动脉造影特点研究
Clinical and coronary angiography characteristics of patients with heart failure preserved ejection fraction combined with type 2 diabetes mellitus
【摘要】 目的分析射血分数保留型心力衰竭(HFpEF)合并T2DM病人的冠状动脉造影术(CAG)结果以及病人的临床特点。方法选取2016年3月至2017年2月青岛大学附属医院心血管内科住院治疗的HFpEF病人165例,根据病人是否合并T2DM,分为T2DM-HFpEF组(n=48)和单纯HFpEF组(n=117),收集并比较2组病人的临床资料、实验室生化指标、CAG及心脏超声结果。结果 T2DM-HFpEF组中女性、NYHA分级Ⅲ~Ⅳ级、高血压、陈旧性心肌梗死、冠状动脉双支及双支以上病变比例均显著高于单纯HFpEF组,差异有统计学意义(P <0. 05)。单纯HFpEF组病人的住院天数、单核细胞计数、Hb水平、前降支(LAD)及回旋支(LCX)狭窄程度均优于T2DM-HFpEF组,差异有统计学意义(P <0. 05)。结论 HFpEF合并T2DM病人的住院时间较单纯HFpEF病人长,其冠状动脉双支及双支以上病变比例较单纯HFpEF病人高,LAD和LCX狭窄程度较单纯HFpEF病人严重。
【Abstract】 Objective To analyze the results of coronary angiography(CAG)and the clinical characteristics of the patients with heart failure preserved ejection fraction(HFpEF)combined with type 2 diabetes mellitus(T2DM). Methods A total of 165 HFpEF patients in the Affiliated Hospital of Qingdao University from March 2016 to February 2017 were enrolled in this study. The patients were divided into T2DM-HFpEF group(n=48)and HFpEF group(n=117)according to whether they presented with T2DM or not. The clinical data,biochemical indicators,CAG and echocardiography results of the two groups were collected and compared. Results The ratio of women,grade Ⅲ-Ⅳ of New York Heart Association(NYHA),hypertension,old myocardial infarction,two and more lesions of the coronary artery in T2DM-HFpEF group was significantly higher than that in HFpEF group(P <0. 05). The duration of hospitalization,the levels of monocyte and hemoglobin,and the stenosis of left anterior descending artery(LAD)and left circumflex(LCX)in HFpEF group were better than those in T2DM-HFpEF group(P < 0. 05). Conclusions Compared with HFpEF patients,T2DM-HFpEF patients have the longer hospitalization days,the larger ratio of people who have two and more lesions of the coronary artery,and the worse stenosis of LAD and LCX.
【Key words】 heart failure preserved ejection fraction; type 2 diabetes mellitus; coronary angiography;
- 【文献出处】 实用老年医学 ,Practical Geriatrics , 编辑部邮箱 ,2020年04期
- 【分类号】R541.6;R587.1
- 【被引频次】3
- 【下载频次】73