【摘要】 目的 :通过对甲状腺结节患者的随访,评估甲状腺结节大小、性质的变化。方法 :在社区451名常住居民中经甲状腺超声检测发现375例甲状腺结节患者,其中男性142例,平均年龄(65.3±8.1)岁,女性233例,平均年龄(62.8±8.3)岁。每年进行随访,为期3年。观察甲状腺结节的个数、结节大小以及对结节性质的初步判断。结果:在随访的3年中,在初次评估的375例甲状腺结节患者的977个甲状腺结节中,发现结节体积有增长的180个,占18.61%。有35例(9.33%)出现新增结节,有6例(1.60%)因发现甲状腺恶性肿瘤而进行了手术治疗。多元logistic回归分析显示,BMI、怀孕次数(女性)、脑力工作者与甲状腺结节体积增长有关(P <0.05)。结论 :大多数甲状腺结节在3年随访期间基本保持结节体积及性质的稳定,并不会对甲状腺结节患者人群的正常生活带来影响。更多还原

【Abstract】 Objective: By following up patients with thyroid nodules, to evaluate the size and nature of thyroid nodules. Methods: Among 451 permanent residents in the community, 375 patients with thyroid nodules were detected by thyroid ultrasound, there were 142 males with an average age of(65.3 ± 8.1) years and 233 females with an average age of(62.8 ± 8.3) years. The patients were followed up every year for 3 years. The number and size of thyroid nodules and the preliminary determination of the nature of nodules were observed. Results: During the 3 years of follow-up, among the 977 thyroid nodules in 375 patients with thyroid nodules in the initial evaluation, 180 nodules were found to have increased in volume, accounting for 18.61%. There were 35 cases(9.33%) with new nodules, and 6 cases(1.60%) underwent surgical treatment due to the discovery of thyroid malignant tumor. Multivariate logistic regression analysis showed that BMI, number of pregnancies(female), and mental workers were related to the increase in the volume of thyroid nodules(P <0.05). Conclusion: Most thyroid nodules remain stable in volume and nature during the 3-year follow-up period, and would not affect the normal life of thyroid nodules patients.更多还原