【摘要】 上皮间质转化(epithelial-mesenchymal transition,EMT)是胃癌发生侵袭转移和多药耐药的重要环节,也是胃癌患者死亡率高的关键因素之一。中药单体具有高效低毒、多靶点、来源广泛等多重优势。本文以EMT相关调控机制为切入点,对近年来中药单体逆转胃癌EMT进行归纳总结,以期为中药单体的研究提供新的思路。更多还原

【Abstract】 Epithelial-mesenchymal transition(EMT) is a key event for gastric cancer invasion and metastasis and multidrug resistance,and it is also one of the important factors for high mortality of gastric cancer patients.Traditional Chinese medicine monomers have multiple advantages such as high efficiency and low toxicity,multiple targets,and wide sources.This article takes the EMT-related regulatory mechanism as the starting point,and summarizes the recent reversal of epithelial-mesenchymal transition in gastric cancer by traditional Chinese medicine monomers in order to provide new ideas for the study of Chinese medicine monomers.更多还原