【摘要】 目的:比较不同粘度骨水泥椎体成形术(PVP)治疗骨质疏松椎体压缩性骨折(OVCF)的临床疗效及生活质量的影响。方法:回顾性分析于2016年8月至2018年2月期间我院收治的104例OVCF患者的临床资料。将患者按数字表法分为对照组(n=52)和研究组(n=52),两组患者均给予PVP治疗,对照组选用低粘度骨水泥,研究组选用高粘度骨水泥。比较两组患者术前、术后1周、术后1个月、术后3个月、术后6个月及术后12个月的Oswestry功能障碍指数(ODI)评分、疼痛视觉模拟量表(VAS)评分、健康状况调查问卷(SF-36)评分以及Cobb角,记录两组并发症发生情况。结果:研究组患者手术时间长于对照组(P<0.05),而两组患者骨水泥注入量、住院时间比较差异无统计学意义(P>0.05)。两组患者术后1周、1个月、3个月、6个月、12个月ODI评分、VAS评分、Cobb角均较术前降低(P<0.05);两组患者术后1个月、3个月、6个月、12个月ODI评分、VAS评分、Cobb角均较术后1周降低(P<0.05);研究组术后1周、1个月、3个月、6个月、12个月ODI评分、VAS评分、Cobb角低于对照组(P<0.05)。两组患者术后1周、1个月、3个月、6个月、12个月SF-36评分均升高,且研究组高于对照组(P<0.05)。两组并发症发生率比较无统计学差异(P>0.05)。结论:高粘度骨水泥应用于PVP治疗OVCF患者疗效确切,可有效减轻患者疼痛状况,改善生活质量,促进患者恢复。更多还原

【Abstract】 Objective: To compare the clinical efficacy of different viscosities of bone cement vertebroplasty(PVP) in the treatment of osteoporotic vertebral compression fractures(OVCF) and its effect of quality of life. Methods: The clinical data of 104 patients with OVCF who were admitted to our hospital from August 2016 to February 2018 were retrospectively analyzed. They were divided into control group(n=52) and study group(n=52) according to the digital table method. Both groups were treated with PVP. The control group was treated with low-viscosity bone cement, and the study group was treated with high-viscosity bone cement. Oswestry dysfunction index(ODI), visual analogue pain scale(VAS), health Questionnaire(SF-36) and Cobb angle were compared between the two groups before operation, 1 week, 1 month, 3 months, 6 months and 12 months after operation. The complications were recorded in both groups.Results: The operation time of the study group was longer than that of the control group(P<0.05), but there were no significant differences in the amount of bone cement injected and hospitalization time between the two groups(P>0.05). The ODI score, VAS score and Cobb angle of 1 week, 1 month, 3 months, 6 months and 12 months after operation in both groups were lower than those before operation(P<0.05). The ODI score, VAS score and Cobb angle of 1 month, 3 months, 6 months and 12 months after operation in both groups were lower than those of 1 week after operation(P<0.05). The ODI score, VAS score and Cobb angle of 1 week, 1 month, 3 months, 6 months,12 months after operation in the study group were lower than those of the control group(P<0.05). The SF-36 scores of the two groups increased at 1 week, 1 month, 3 months, 6 months and 12 months after operation, and the SF-36 scores of the study group were higher than those of the control group(P<0.05). There was no significant difference in the incidence of complications between the two groups(P>0.05). Conclusion: The application of high viscosity bone cement in the treatment of OVCF patients with PVP has a definite effect,which can effectively relieve the pain, and it can improve the quality of life, and promote the recovery of patients.更多还原