【摘要】 目的本研究旨在探索广东省名老中医黄春林教授"调脾泄浊方"对腹膜透析患者胃肠道症状的改善作用。方法选取2017年12月至2018年12月在广东省中医院腹透门诊规律随访的维持性腹膜透析患者59例,随机分为中药组29例,对照组30例。中药组给予常规治疗+调脾泄浊方,对照组给予常规治疗+益生菌。观察两组患者的临床疗效,比较其胃肠道症状积分和中医证候积分结果,检测安全性指标,如实记录不良反应情况。结果中药组患者的胃肠道积分和中医证候积分均显著下降,起到缓解腹胀、改善食欲以及软化大便等作用,并且未见不良反应。结论与益生菌相比,"调脾泄浊方"对腹透患者胃肠道症状具有显著的改善作用。更多还原

【Abstract】 Objective To evaluate the clinical effect and safety of Professor Huang Chunlin′s prescription for regulating spleen and relieving turbid to improve gastrointestinal function in peritoneal dialysis(PD) patients. Methods Randomized controlled trial(RCT) was conducted among 59 cases of children with PD patients from PD clinic of Guangdong Provincial Hospital of Chinese Medicine from December 2017 to December 2018. The patients were randomly divided into a Chinese medicine group(n = 29) and control group(n = 30). The Chinese medicine group was given Tiaopi Xiezhuo Formula combined with basic treatment, and the control group was treated by Bifidobacterium and basic treatment. Evaluation was given on the total clinical efficacy, gastrointestinal symptom rating scale(GSRS), TCM syndrome score and medication safety. Adverse reactions should be truthfully recorded. Results The GSRS score and TCM syndrome score of the Chinese medicine group were significantly decreased, which alleviated abdominal distension,improved appetite and softened stools, and no adverse reactions were observed. Conclusion Compared with Bifidobacterium, Tiaopi Xiezhuo Formula can significantly improve gastrointestinal symptoms in PD patients.更多还原