【摘要】 目的探究分析H型高血压与腹主动脉瘤发生的相关性,为临床早期诊治腹主动脉瘤提供参考依据。方法选择2018年11月—2019年10月在该院健康体检的1 000名老年人设为健康组;选择同期该院收治的1 000例单纯高血压老年患者设为非H型高血压组;另选择同期该院收治的1 000例H型高血压老年患者设为H型高血压组,均进行腹主动脉超声筛查,对比3组腹主动脉瘤的发生率。并采用多元Logistic回归分析H型高血压患者发生腹主动脉瘤的风险。结果 H型高血压组的腹主动脉瘤发生率9.80%显著高于健康组0.30%、非H型高血压组1.80%,差异有统计学意义(χ~2=136.945,P<0.05)。H型高血压组腹主动脉瘤患者的腹主动脉瘤体的最大直径(57.34±6.63)mm,显著大于健康组(33.00±2.00)mm、非H型高血压组(45.47±6.24)mm的患者,差异有统计学意义(F=37.933,P<0.05)。经多元Logistic回归分析显示,H型高血压组较非H型高血压组发生腹主动脉瘤的风险增加4.08倍(OR=4.514,95%CI:0.798～5.722,P=0.011)。结论 H型高血压患者发生腹主动脉瘤的风险较大,故临床需积极控制患者的血同型半胱氨酸水平,预防或减少腹主动脉瘤发生。更多还原

【Abstract】 Objective To explore and analyze the correlation between H-type hypertension and abdominal aortic aneurysm, so as to pro-vide a reference for early clinical diagnosis and treatment of abdominal aortic aneurysm. Methods The 1 000 elderly people who had a physical examination in the hospital from November 2018 to October 2019 were selected as the healthy group; 1 000 elderly patients with isolated hypertension admitted to the hospital during the same period were selected as the non-H-type hypertension group; an-other option during the same period, 1 000 elderly patients with H-type hypertension admitted to the hospital were set as H-type hy-pertension group, and all were screened by abdominal aortic ultrasound to compare the incidence of abdominal aortic aneurysms in the three groups. Multivariate Logistic regression was used to analyze the risk of abdominal aortic aneurysm in patients with H-type hypertension. Results The incidence of abdominal aortic aneurysm in the H-type hypertension group 9.80% was significantly higher than that of the healthy group 0.30% and the non-H-type hypertension group 1.80%, and the difference was statistically significant(χ~2=136.945, P<0.05). The maximum diameter of the abdominal aortic aneurysm in patients with abdominal aortic aneurysm in the Htype hypertension group was(57.34±6.63) mm, which was significantly larger than that of the healthy group(33.00±2.00) mm and the non-H-type hypertension group(45.47±6.24) mm,the difference was statistically significant(F=37.933, P<0.05). Multivariate logistic regression analysis showed that the risk of abdominal aortic aneurysm in the H-type hypertension group was 4.08 times higher than that of the non-H-type hypertension group(OR=4.514, 95% CI: 0.798～5.722, P=0.011). Conclusion Patients with type H hypertension have a higher risk of abdominal aortic aneurysm. Therefore, it is necessary to actively control the blood homocysteine level of patients in clinical practice to prevent or reduce the occurrence of abdominal aortic aneurysm.更多还原