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慢性乙型肝炎中医体质与HBV-DNA载量相关性分析

Analysis of correlativity between TCM constitution and HBV-DNA load of chronic hepatitis B

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【作者】 张健荣李民章瑾孙学娟浦佩珉顾尔莉章幼奕

【Author】 ZHANG Jian-rong;LI Min;ZHANG Jin;Nantong Third People’s Hospital,Jiangsu Province;

【通讯作者】 李民;

【机构】 江苏省南通市第三人民医院江苏省海安县第三人民医院南京中医药大学第一临床医学院

【摘要】 目的:通过调查慢性乙型肝炎患者中医体质与HBV-DNA载量的相关性,为临床治疗和预防提供参考。方法:根据中华中医药学会"中医体质分类判定标准",对诊断为慢性乙型肝炎的263例患者中医体质进行调查,同时检测患者HBV-DNA载量。结果:被调查患者中,湿热质(25.4%)、气虚质(22.9%)、气郁质(22.1%)、痰湿质(17.0%)、阴虚质(4.2%)、瘀血质(7.6%)、阳虚质(0.8%)、平和质(0.0%)、特禀质(0.0%),不同中医体质类型中HBV-DNA载量不同。且慢性乙型肝炎患者以湿热质、气虚质、气郁质、痰湿质患者为主,其HBV-DNA载量多数大于1×10~3拷贝/mL。结论:中医体质类型以湿热质、气虚质、气郁质和痰湿质为主,不同体质HBV患者HBV-DNA载量也不同,为不同体质患者采取不同治疗方式提供参考。

【Abstract】 Objective:To investigate the correlativity between TCM constitution and HBV-DNA load of patients with chronic hepatitis B,in order to provide the reference for clinical treatment and prevention.Methods:According to "Criteria for Classification and Determination of Constitution in TCM" of China Association of Chinese Medicine,TCM constitutions of 263 patients diagnosed as chronic hepatitis B were investigated,and HBV-DNA load of patients was tested at the same time.Results:The patients under investigation,damp-heat constitution(25.4%),qi-deficiency constitution(22.9%),qi-stagnation constitution(22.1%),phlegm-dampness constitution(17.0%),yin-deficiency constitution(4.2%),and blood-stasis constitution(7.6%),yang-deficiency constitution(0.8%),yin-yang harmony constitution(0.0%),allergic constitution(0.0%).HBV-DNA load was different in different TCM constitution types.The patients with chronic hepatitis B were mainly characterized by damp-heat constitution,qi-deficiency constitution,qi stagnation constitution,phlegm-dampness constitution;and their HBV-DNA load was mostly greater than 1×10~3 copy/m L.Conlusion:TCM constitution types of patients with chronic hepatitis B are mainly damp-heat constitution,qi deficiency constitution,qi stagnation constitution and phlegm-dampness constitution;HBV patients with different constitution have different HBV-DNA loads,which provides a reference for patients with different constitutions and different treatment methods.

【基金】 第三批江苏省中医临床优秀人才研修项目;南通市社会发展计划项目(编号:HS2014079、GJZ16104);南通市卫生计生委局青项目(编号:WQ2014037)
  • 【文献出处】 山西中医 ,Shanxi Journal of Traditional Chinese Medicine , 编辑部邮箱 ,2020年10期
  • 【分类号】R259
  • 【被引频次】4
  • 【下载频次】69
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