【摘要】 目的了解2006-2017年北京市急性弛缓性麻痹(acute flaccid paralysis,AFP)病例中短暂性肢体麻痹病例流行病学分布和临床特征。方法利用2006-2017年北京市AFP病例监测资料,对AFP病例中临床诊断为短暂性肢体麻痹的病例进行描述性分析。结果 2006-2017年,北京市共报告AFP确诊病例380例,其中50例(13. 2%)临床诊断为短暂性肢体麻痹,门诊和住院病例比为3. 6∶1,男女性别比为2. 3∶1,0～4岁39例(39/50),病例分布无地区性和季节性。45例(45/50)病例肌力下降,受累部位以单下肢为主,18例(18/50)病例受累侧肌张力降低; 28例(28/50)病例深部腱反射减弱或消失。肌力、肌张力和深部腱反射三项均有异常者8例(8/50),两项有异常者25例(25/50),一项有异常者17例(17/50)。22例(22/50)伴有发热,9例(9/50)伴有腹泻,7例(7/50)麻痹部位伴有肌肉疼痛。所有病例麻痹后60～70 d均无残留麻痹,麻痹与恢复时间间隔中位数为9 d。结论 AFP病例中短暂性肢体麻痹较为常见,多数症状较轻,病程较短,全部预后较好,AFP病例麻痹恢复情况的随访观察为短暂性肢体麻痹的临床诊断提供了重要依据。更多还原

【Abstract】 Objective To understand the epidemiological distribution and clinical characteristics of transient limb paralysis in acute flaccid paralysis( AFP) cases in Beijing from 2006 to 2017. Methods Descriptive epidemiological analysis of the transient limb paralysis cases in AFP cases was conducted by using the AFP cases surveillance data in Beijing during this period. Results A total of 380 AFP cases were reported in Beijing from 2006 to 2017. Among them,50 AFP cases were clinically diagnosed as transient limb paralysis. The ratio of outpatient to inpatient was 3. 6 ∶ 1. The ratio of male to female was2. 3 ∶ 1. 39 cases( 39/50) were 0-4 years old. There was no regional and seasonal distribution of these cases. 45 cases( 45/50) suffered from decreased muscle strength,mainly in one lower limb. 18 cases( 18/50) suffered from decreased muscle tension on the affected side. 28 cases( 28/50) suffered from decrease or disappearance of deep tendon reflex. 8 cases( 8/50)had three abnormal symptoms of muscle strength,muscle tension and deep tendon reflex,25 cases( 25/50) had two abnormal symptoms and 17 cases( 17/50) had one abnormal symptom. 22 cases( 22/50) had fever,9 cases( 9/50) had diarrhea and 7 cases( 7/50) cases had muscle pain. There was no residual paralysis in all cases 60-70 days after paralysis. The median interval between paralysis and recovery was 9 days. Conclusions Transient limb paralysis case were common in AFP cases.Most of cases had mild symptoms and shorter disease course. All cases had better prognosis. Follow-up observation of the paralysis recovery provided an important basis for the clinical diagnosis of transient limb paralysis.更多还原