【摘要】 【目的】观察雷火灸治疗结直肠癌术后疲劳综合征的临床疗效,并探讨雷火灸在加速康复外科理念治疗结直肠癌术后疲劳综合征中的应用价值。【方法】将63例结直肠癌术后疲劳综合征患者随机分为观察组和对照组,其中,观察组31例、对照组32例;对照组采取围手术期加速康复外科干预措施;观察组采取围手术期加速康复外科干预措施,联合雷火灸双侧足三里、三阴交疗法。每天治疗1次,以术后7 d为1个疗程。观察2组患者治疗前后视觉模拟量表(VAS)评分、简明心境状态量表(POMS)评分、围手术期疲劳评定量表(ICFS)评分的变化情况,比较2组患者治疗前后淋巴细胞计数(TLC)、C-反应蛋白(CRP)、血清总蛋白(TP)、血清白蛋白(ALB)含量的情况,并评价2组患者的临床疗效。【结果】(1)治疗后,2组患者的VAS、POMS、ICFS评分均明显改善(P<0.05),且观察组在改善VAS、POMS、ICFS评分方面明显优于同期对照组,差异有统计学意义(P<0.05)。(2)治疗后第3天,观察组愈显率为19.35%(6/31),对照组为3.13%(1/32);观察组总有效率为96.77%(30/31),对照组为96.88%(31/32);观察组愈显率稍高于对照组,但观察组愈显率及总有效率与对照组比较,差异均无统计学意义(P>0.05)。治疗后第7天,观察组愈显率为96.77%(30/31),对照组为71.88%(23/32);观察组总有效率为100.00%(31/31),对照组为100.00%(32/32);观察组愈显率优于对照组,差异有统计学意义(P<0.05),2组总有效率相同,差异无统计学意义(P>0.05)。(3)治疗后,2组患者的TLC、CRP、TP、ALB水平均明显改善(P<0.05),但观察组与同期对照组比较,差异均无统计学意义(P>0.05)。【结论】雷火灸治疗结直肠癌术后疲劳综合征,可以显著改善患者的疲劳症状,有助于患者的术后快速康复,疗效显著。更多还原

【Abstract】 Objective To observe the clinical efficacy of moxibustion with immediate effect for the treatment of postoperative fatigue syndrome of colorectal cancer, and to explore the application value of moxibustion with immediate effect for the treatment of postoperative fatigue syndrome of colorectal cancer in enhanced recovery after surgery(ERAS)field. Methods Sixty-three patients with postoperative fatigue syndrome of colorectal cancer were randomly divided into observation group(31 cases) and control group(32 cases). The both groups received perioperative-period ERAS interventions, additionally, the observation group received moxibustion with immediate effect at bilateral Zusanli(ST36)and Sanyinjiao(SP6)points,once per time,postoperative 7 days constituted one course. The changes in visual analogue scale(VAS)score,profile of mood states(POMS)score,and identity-consequence fatigue scale(ICFS)score were observed in the two groups before and after treatment,the T-Lymphocyte count(TLC),and the contents of C-reactive protein(CRP),serum total protein(TP),and serum albumin(ALB)were compared in the two groups before and after treatment,and the clinical efficacy was evaluated. Results(1)After treatment, the VAS, POMS, ICFS scores in the two groups were significantly improved(P < 0.05), and the improvement in VAS, POMS, ICFS scores of the observation group was significantly superior to that of the control group at the same time(P < 0.05).(2)On day 3 after treatment,the markedly effective rate was 19.35%(6/31)in the observation group,and 3.13%(1/32)in the control group. The total effective rate was 96.77%(30/31)in the observation group,and 96.88%(31/32)in the control group. The markedly effective rate in the observation group was higher than that in the control group, but there were no significant differences in the markedly effective rate and total effective rate in the two groups(P>0.05). On day 7 after treatment,the markedly effective rate was 96.77%(30/31)in the observation group,and 71.88%(23/32)in the control group. The total effective rate was 100.00%(31/31)in the observation group,and 100.00%(32/32)in the control group. The markedly effective rate in the observation group was superior to that in the control group(P <0.05),but there was no significant difference in the total effective rate in the two groups(P>0.05).(3)After treatment,the levels of TLC,CRP,TP,ALB in the two groups were significantly improved(P < 0.05),but were insignificantly different as compared with those of the control group at the same time(P < 0.05). Conclusion Moxibustion with immediate effect is effective for the treatment of postoperative fatigue syndrome of colorectal cancer,and can improve fatigue symptoms in the patients and help the patients recover quickly after surgery.更多还原