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祛寒除痹汤联合双氯芬酸钠治疗类风湿性关节炎临床研究
Clinical Study on Quhan Chubi Tang Combined with Diclofenac Sodium for Rheumatoid Arthritis
【摘要】 目的:观察祛寒除痹汤联合双氯芬酸钠治疗类风湿性关节炎的临床疗效。方法:将类风湿性关节炎60例随机分为对照组和观察组,每组各30例;对照组给予双氯芬酸钠治疗,观察组在对照组治疗的基础上加用祛寒除痹汤治疗,2组均以7 d为1个疗程,共治疗4个疗程;观察比较2组临床疗效,治疗前后患者晨僵时间、关节疼痛数量、关节红肿数量变化及血沉(ESR)、类风湿因子(RF)水平变化。结果:总有效率观察组为90.00%,对照组为66.67%,2组比较,差异有统计学意义(P<0.05)。治疗后,观察组患者晨僵时间短于对照组,关节疼痛、关节红肿数量少于对照组,2组比较,差异均有统计学意义(P<0.05)。治疗后,观察组血清ESR、RF水平均明显低于对照组,2组比较,差异均有统计学意义(P<0.05)。结论:祛寒除痹汤联合双氯芬酸钠治疗类风湿性关节炎疗效肯定,效果优于单纯双氯芬酸钠治疗。
【Abstract】 Objective:To observe the clinical effect of Quhan Chubi tang combined with diclofenac sodium for rheumatoid arthritis. Methods:A total of 60 cases of patients with rheumatoid arthritis were randomly divided into the control group and the observation group,30 cases in each group. The control group was treated with diclofenac sodium,and the observation group was additionally treated with Quhan Chubi tang based on the treatment of the control group. Both groups were treated for four courses,seven days being a course. The changes in the time of morning stiffness,in the numbers of joint pain and red swelling respectively, and in the levels of erythrocyte sedimentation rate(ESR) and rheumatoid factors(RF) before and after treatment and clinical effect in the two groups were observed and compared. Results: The total effective rate was 90.00% in the observation group and 66.67% in the control group,the difference being significant(P<0.05). After treatment,the time of morning stiffness in the observation group was shorter than that in the control group;the numbers of joint pain and red swelling respectively were fewer than those in the control group;the comparisons between the two groups showed significant differences(P<0.05). After treatment, the levels of ESR and RF in serum in the observation group were significantly lower than those in the control group,differences being significant(P<0.05). Conclusion:The therapy of Quhan Chubi tang combined with diclofenac sodium has definite clinical effect in treating rheumatoid arthritis,whose effect is better than that of simple diclofenac sodium.
【Key words】 Rheumatoid arthritis; Integrated Chinese and western medicine therapy; Quhan Chubi tang; Diclofenac sodium;
- 【文献出处】 新中医 ,Journal of New Chinese Medicine , 编辑部邮箱 ,2020年13期
- 【分类号】R593.22
- 【被引频次】1
- 【下载频次】103