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新型冠状病毒肺炎临床分型与影像特点分析

Clinical classification and CT imaging features of corona virus disease-2019

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【作者】 丁国勇贾玉柱吕明权郑康春张万里项光涨

【Author】 DING Guoyong;JIA Yuzhu;LYV Mingquan;Department of Radiology,First People’s Hospital,Longwan District,Wenzhou;

【通讯作者】 张万里;

【机构】 温州市龙湾区第一人民医院放射科浙江省立同德医院放射科温州市中心医院集团第六医院放射科温州市龙湾区第一人民医院感染科温州市龙湾区第一人民医院内科

【摘要】 目的探讨新型冠状病毒肺炎(COVID-19)的临床分型和影像征象特点。方法回顾性分析53例经临床证实COVID-19患者的临床和影像征象资料,依据《COVID-19诊疗方案》(第七版试行)临床分型分组,比较普通型与轻型、重型、危重型的临床特征和实验室指标差异,并比较普通型与重型、危重型的影像特征。结果临床资料中COVID-19普通型患者的年龄小于危重型(t=76.15,P<0.05),呼吸困难发生率明显低于危重型,C反应蛋白增高异常高于轻型(P均<0.05);普通型患者的白细胞异常和淋巴细胞减低均高于轻型,但低于重型、危重型(P均<0.05)。普通型COVID-19患者更倾向于多肺叶累及(P<0.05);铺路石征征象多见重症、危重症,均高于普通型(P均<0.05),其他间接征象中胸腔积液多为危重症者(P<0.05),而淋巴结肿大在三型中少见(P>0.05)。结论在COVID-19的诊断中临床表现、实验室检查和CT表现具有一定特征性,诊断时应结合患者流行病学史、临床表现和影像特征才能够更为精准地诊断COVID-19。

【Abstract】 Objective To explore the clinical classification and imaging characteristics of corona virus disease-2019(COVID-19).MethodsThe data of clinical and imaging of 53 patients who confirmed COVID-19 were retrospectively analyzed.According to the clinical classification of the "diagnosis and treatment guideline of COVID-19"(7 th edition),the clinical characteristics and laboratory indicators among general group,mild group,severe group,and critical group were compared.ResultsThe general type of patients with COVID-19 were younger than patients with critical type(t=76.15,P<0.05),the incidence of dyspnea was significantly lower than that of patients with critical type,and C-reactive protein was abnormally higher than patients with mild type(P<0.05).The leukocyte abnormalities and lymphopenia were lower in general type patients than in mild type patients,but lower than those in severe type and critical type patients(P<0.05).General type of COVID-19 were more likely to have multilobe involvement(P<0.05);signs of paving stones were more common in patients with severe and critical types,which were higher than those of the patients with general type(P<0.05).In other indirect signs,pleural effusion was more common in patients with critical type(P<0.05),but lymphadenopathy was rare in patients with mild,severe,and critical types(P>0.05).ConclusionIn the diagnosis of COVID-19,the clinical characteristics,laboratory indexes and CT imaging have some characteristics.The diagnosis of covid-19 should be combined with the epidemiological history,clinical characteristics and imaging.

【基金】 浙江省基础公益研究计划项目(LGF18H180016)
  • 【文献出处】 全科医学临床与教育 ,Clinical Education of General Practice , 编辑部邮箱 ,2020年03期
  • 【分类号】R563.1;R816.4
  • 【下载频次】128
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