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基于级联卷积神经网络的前列腺磁共振图像分类

Prostate Cancer Diagnosis Based on Cascaded Convolutional Neural Networks

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【作者】 刘可文刘紫龙汪香玉陈黎李钊吴光耀刘朝阳

【Author】 LIU Ke-wen;LIU Zi-long;WANG Xiang-yu;CHEN Li;LI Zhao;WU Guang-yao;LIU Chao-yang;School of Information Engineering, Wuhan University of Technology;State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan(Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences);Department of Radiology, The First Affiliated Hospital of Shenzhen University;Department of Radiology, Shenzhen University General Hospital;

【通讯作者】 刘可文;

【机构】 武汉理工大学信息工程学院波谱与原子分子物理国家重点实验室武汉磁共振中心(中国科学院精密测量科学与技术创新研究院)深圳市第二人民医院医学影像科深圳大学总医院医学影像科

【摘要】 针对深度学习训练成本高,以及基于磁共振图像的前列腺癌临床诊断需要大量医学常识且极为耗时的问题,本文提出了一种基于级联卷积神经网络(Convolutional Neural Network,CNN)和磁共振图像的前列腺癌(Prostate Cancer,PCa)自动分类诊断方法,该网络以Faster-RCNN作为前网络,对前列腺区域进行提取分割,用于排除前列腺附近组织器官的干扰;以基于ResNet改进的网络结构CNN40bottleneck作为后网络,用于对前列腺区域病变进行分类.后网络由瓶颈结构串联组成,其中使用批量标准化(Batch Normalization,BN)、全局平均池化(Global Average Pooling,GAP)进行优化.实验结果证明,本文方法对前列腺癌诊断结果较好,而且缩减了训练时间和参数量,有效降低了训练成本.

【Abstract】 Interpreting magnetic resonance imaging(MRI) data by radiologists is time consuming and demands special expertise. Diagnosis of prostate cancer(PCa) with deep learning can also be time consuming and data storage consuming. This work presents an automated method for PCa detection based on cascaded convolutional neural network(CNN), including pre-network and post-network. The pre-network is based on a Faster-RCNN and trained with prostate images in order to separate the prostate from nearby tissues; the ResNet-based post-network is for PCa diagnosis, which is connected by bottlenecks and improved by applying batch normalization(BN) and global average pooling(GAP). The experimental results demonstrated that the cascaded CNN proposed had a good classification results on the in-house datasets, with less training time and computation resources.

【基金】 国家重点研发计划资助项目(2018YFC0115100)
  • 【文献出处】 波谱学杂志 ,Chinese Journal of Magnetic Resonance , 编辑部邮箱 ,2020年02期
  • 【分类号】R445.2;TP183;TP391.41
  • 【被引频次】9
  • 【下载频次】163
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