【摘要】 目的:探讨肥厚型心肌病(HCM)患者晕厥发生的相关因素。方法:回顾性收集78例HCM患者的临床资料,根据有无发生晕厥,分为晕厥组(22例)和无晕厥组(56例),统计分析2组相关指标。结果:HCM患者晕厥组年龄较无晕厥组偏高[(59.6±10.3)岁vs (50.2±14.5)岁,P=0.007]; N末端脑钠肽前体水平较无晕厥组偏低[(1031.4±1959.3) ng/L vs(3063.8±3847.8) ng/L,P=0.02];心率较无晕厥组偏低[(64.9±13.5)次/min vs(76.6±23.2)次/min,P=0.01];房性早搏数目较无晕厥组高[(257.8±392.1)次/d vs(96.4±325.5)次/d,P=0.02];房性心动过速发生率较无晕厥组高(45.5%vs 21.4%,P=0.03)。2组影像学指标比较,差异无统计学意义。Logistic回归分析显示,年龄、心率、房性心动过速发生率是晕厥的相关危险因素。结论:年龄、心率、房性心动过速发生率是HCM患者发生晕厥的相关危险因素。更多还原

【Abstract】 Objective: To investigate the related factors of syncope in patients with hypertrophic cardiomyopathy( HCM). Methods: The clinical data of 78 patients with HCM were retrospectively collected,and the patients were divided into syncope group( 22 cases) and non-syncope group( 56 cases). The related indicators were statistically analyzed in two groups. Results: The age in syncope group was significantly older than that in non-syncope group [( 59. 6 ± 10. 3) years vs( 50. 2 ± 14. 5) years,P = 0. 007]. The level of N-terminal pro-brain natriuretic peptide was significantly lower in syncope group than that in the non-syncope group [( 1031. 4 ± 1959. 3) ng/L vs( 3063. 8 ± 3847. 8) ng/L,P = 0. 02]. Heart rate was significantly lower in syncope group than that in non-syncope group [( 64. 9 ± 13. 5) beats/min vs( 76. 6 ± 23. 2)beats/min,P = 0. 01]. The number of premature atrial beats was significantly greater in syncope group than in non-syncope[( 257. 8 ± 392. 1) beats vs( 96. 4 ± 325. 5) beats,P = 0. 02]. The number of patients with atrial tachycardia was significantly greater in syncope group than that in non-syncope group( 45. 5% vs 21. 4%,P = 0. 03). There was no significant difference in imaging indexes between the two groups. Logistic regression analysis showed that age,heart rate,and number of atrial tachycardia cases were related risk factors for syncope. Conclusion: Age,heart rate,and number of atrial tachycardia cases were the related risk factors for syncope in HCM patients.更多还原