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川产竹叶柴胡芦丁与总黄酮醇苷的含量测定

Determination of rutin and total flavonol glycosides in Zhuyechaihu

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【作者】 闫婕龙飞周元雳刘慧卫莹芳裴瑾

【Author】 YAN Jie;LONG Fei;ZHOU Yuan-li;LIU Hui;WEI Ying-fang;PEI Jin;School of Pharmacy,Chengdu University of Traditional Chinese Medicine;Key Laboratory of Standardization for Chinese Herbal Medicine,Ministry of Education;Key laboratory of Characteristic Chinese Medicine Resources in Southwest China;Sichuan Kangtenang Pharmaceutical Co.,Ltd.;

【通讯作者】 裴瑾;

【机构】 成都中医药大学药学院中药材标准化教育部重点实验室西南特色中药资源国家重点实验室培育基地四川康特能药业有限公司

【摘要】 目的:科学评价竹叶柴胡药材质量。方法:采用高效液相色谱法,测定不同品种、产地、部位竹叶柴胡药材的芦丁及总黄酮醇苷的含量。结果:不同样品根中黄酮含量极低,地上部分的芦丁含量在0.34~1.55%之间,总黄酮醇苷的含量在2.82~7.37%之间。结论:竹叶柴胡地上部分与根应分别入药并建立相应质量标准,总黄酮醇苷含量测定可以更科学的评价竹叶柴胡的药材质量。

【Abstract】 Objective:This study was conducted to evaluate the quality of Zhuyechaihu scientifically based on the flavonoid content.Method:Contents of rutin and total flavonol glycosides in different varieties,origins and parts of Zhuyechaihu were detected by HPLC.Result:The content of flavonoids in roots was very low.The contents of rutin and total flavonol glycosides in aerial parts were 0.34-1.55% and 2.82-7.37%,respectively.Conclusion:The different parts of Zhuyechaihu should be used separately and the corresponding quality standards should be established.The determination of total flavonol glycosides can evaluate the quality of Zhuyechaihu more scientifically.

【基金】 国家自然科学基金委青年科学基金项目(81503200);四川省科技厅应用基础研究计划项目(2019YJ0333);成都中医药大学“杏林学者”学科人才科研提升计划(QNXZ2018015,CXTD2018016);四川省教育厅高校科研创新团队(18TD0017)
  • 【文献出处】 中药与临床 ,Pharmacy and Clinics of Chinese Materia Medica , 编辑部邮箱 ,2020年05期
  • 【分类号】R284.1
  • 【被引频次】1
  • 【下载频次】376
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