【摘要】 目的 探讨肝硬化严重程度与焦虑抑郁情绪的相关性。方法 将108例肝硬化患者根据肝功能Child-Pugh评分分级标准分为A级42例、B级36例、C级30例,采用焦虑自评量表评定焦虑状况,抑郁自评量表评定抑郁状况,对评定结果进行相关分析。结果 本组108例肝硬化患者焦虑抑郁总检出率为52.8%,其中焦虑检出率为30.6%,抑郁检出率为38.0%,焦虑抑郁共存检出率为15.7%;肝功能Child-Pugh不同分级中焦虑、抑郁、焦虑抑郁共存、焦虑抑郁总检出率、焦虑自评量表评分、抑郁自评量表评分及抑郁指数依次为C级>B级>A级,差异均有统计学意义(P<0.05或0.01);Pearson相关分析显示肝硬化患者肝功能Child-Pugh分级与焦虑自评量表评分、抑郁指数均呈显著正相关(P<0.01)。结论 肝硬化患者严重程度及肝功能Child-Pugh评分与焦虑抑郁状况呈直线正相关,疾病程度越严重、肝功能Child-Pugh评分越高、焦虑抑郁状况越严重。更多还原

【Abstract】 Objective To explore the correlation between the severity of liver cirrhosis and negative emotions with depression or anxiety.Methods 108 patients with liver cirrhosis were divided into grade A(42 cases),grade B(36 cases),and grade C(30 cases)according to the liver function Child-Pugh score classification criteria.SAS was used to assess anxiety status,SDS was used to assess depression status,and the assessment results were analyzed.Results The total detectable rate of negative emotions with depression or anxiety in 108 liver cirrhosis patients was 52.8%,that of anxiety and depression were 30.6 % and38.0% respectively,the patients both depression and anxiety accounted for 15.7%.The detetectable rates of negative emotions with anxiety,depression,depression and(or) anxiety,SAS,SDS,SDS depression index in liver cirrhosis as Child-Pugh grade C,B and A were significantly different respectively,grade C>grade B>grade A(P<0.05 or 0.01).Pearson correlation analysis showed that Child-Pugh classification of liver function in patients with liver cirrhosis was significantly positively correlated with SAS and SDS depression index( P<0.01).Conclusions The severity of liver cirrhosis and liver function Child-Pugh score are linearly positively correlated with anxiety and depression.The more severe the disease,the higher the liver function Child-Pugh score and the more serious the anxiety and depression status.更多还原