【摘要】 目的探讨哮喘患儿睡眠障碍与注意缺陷多动障碍的特点及关联性。方法选择6～14岁哮喘慢性持续期患儿35例,通过肺功能及哮喘控制测试评分(ACT)分为哮喘基本控制组和未控制组。对患儿进行儿童睡眠紊乱量表评分和夜间睡眠监测,并完成视听整合持续操作测试(IVA-CPT)和戴斯-纳格利尔里认知评估系统(D-N:CAS)检测。结果两组的儿童睡眠紊乱量表(SDSC)总粗分、入睡或维持睡眠障碍、睡眠-觉醒转换障碍、睡眠出汗过多指标比较差异有统计学意义(P<0.01)。夜间睡眠监测参数多项指标两组比较差异有统计学意义(P<0.05)。IVA-CPT检测哮喘未控制组综合反应控制力商数(FSCQ)、综合注意力商数(FSAQ)较哮喘基本控制组明显减低(P<0.01);D-N:CAS参数指标中哮喘基本控制组和哮喘未控制组患儿的计划力(PLAN)、同时性加工能力(SIM)、注意力(ATT)、继时性加工能力(SUC)、认知水平得分(FS),比较均有统计学意义(P<0.05)。IVA-CPT指标中FSCQ、FSAQ和D-N:CAS中PLAN、SIM、ATT、SUC、FS与睡眠参数中的SDSC总粗分、入睡或维持障碍、睡眠-觉醒转换障碍、AHI呈负相关(均P<0.05),与睡眠效率、最低血氧呈正相关(均P<0.05)。结论哮喘患儿易出现睡眠结构紊乱和注意缺陷多动障碍,两者存在关联性影响。更多还原

【Abstract】 Objective To explore the characteristics and correlation of sleep disorders and attention deficit hyperactivity disorder in children with asthma. Methods Thirty-five children aged 6 to 14 with chronic duration of asthma were selected and divided into asthma basic control group and asthma non-control group according to the lung function and asthma control test(ACT) scores. The children’s sleep disorder scale was scored and their night-time sleep monitoring was performed. The integrated visual and auditory continuous performance test(IVA-CPT) and Das-Naglieri cognitive assessment system(D-N:CAS) were completed. Results There were significant differences in the indicators of Sleep Disturbances Scale for Children(SDSC) total score, disorders of initiating or maintaining sleep, sleep-wake transition disorders and excessive sleep sweating between two groups(P<0.01). There were significant differences in the night sleep monitoring parameters between two groups(P<0.05). Full scale response control quotient(FSCQ) and full scale attention quotient(FSAQ) in asthma non-control group detected by IVA-CPT were significantly lower than those in basic control group(P<0.01). Among the D-N: CAS parameters, there were significant differences in planning ability(PLAN), simultaneous processing ability(SIM), attention ability(ATT), successive processing ability(SUC) and full cognition score(FS) of children between two groups(P<0.05). FSCQ and FSAQ in IVA-CPT parameters and PLAN, SIM, ATT, SUC and FS in D-N: CAS parameters were negatively correlated with SDSC total score, disorders of initiating or maintaining sleep, sleep-wake transition disorders and AHI in the sleep parameters(all P<0.05), and positively correlated with sleep efficiency and lowest blood oxygen value(all P<0.05). Conclusion Children with asthma are prone to sleep structure disorder and attention deficit hyperactivity disorder, which are related to each other.更多还原