【摘要】 我国已经进入慢病时代,医药学专业需要加强与慢病相关的医药学人才的培养。但是现行医药学相关专业慢病药物的相关药理学实验开设极少,同时使用传统的模式生物如小鼠等存在诸多缺陷。针对慢病药物开设相关的药理学实验和引入新的模型生物势在必行。模式生物斑马鱼用于慢病药物药理研究具有诸多优势,可以用于开设多种慢病药物的药理学实验课。文章系统论证了慢病药物药理学实验开设的必要性和所存在的问题,并把斑马鱼作为模式生物用于慢病药物药理学实验,阐述了引入斑马鱼实验的必要性和优势,进行了慢病药物药理学实验设计,分析了斑马鱼在慢病药物药理学实验教学中暴露出来的问题,并提出了解决方案,为今后更好地开展相关实验教学工作提供经验和依据。更多还原

【Abstract】 China has entered the era of chronic disease, and the medical and pharmaceutical major needs to strengthen the training of medical and pharmaceutical talents related to chronic disease. Pharmacology Experiment is a required course for medical science and pharmacy majors, which plays an important role in cultivating students’ professional knowledge and thinking. However, there are few pharmacological experiments related to chronic disease drugs, and the traditional model organisms such as mice have many defects. It is necessary to set up the courses of Pharmacology Experiment and introduce new model organisms for chronic disease drugs. Zebra fish has many advantages in pharmacology research of chronic disease drugs, which can be used to set up a variety of experiment courses of pharmacology of chronic disease drugs. This paper discusses the necessity and the existing problems of Pharmacology Experiment course teaching related to chronic disease, and the introduction of zebra fish as a model organism for pharmacology experiment related to chronic disease, expounds the necessity and advantages of zebra fish experiment, analyzes the possible problems, and puts forward some solutions to the problems, which provides experience and basis for better conduction of related experiment teaching in the future.更多还原