【摘要】 目的根据真实血栓的实验数据,建立血栓流变学黏度模型,初步实现血栓分类。方法采用旋转式流变仪检测离体1 h血栓黏度与剪切速率的关系。通过实验数据拟合已知的黏度模型。结果血栓流变学实验表明,血栓呈剪切变稀的假塑性流体特征,采用幂律方程和Herschel-Bulkley方程拟合血栓黏度随剪切速率变化曲线,发现Herschel-Bulkley方程拟合精度更高;在此基础上,对方程中初始屈服应力（τ₀）参数进行讨论和分析,以τ₀=500 Pa为指标初步划分了血栓类型。结论从某种意义上为临床取栓提供了生物力学判断依据,为研究血栓内部成分提供了理论参考。更多还原

【Abstract】 Objective Based on the experimental data of real thrombus to establish a rheological viscosity model of thrombus for making the classification of thrombus. Methods By using rotary rheometer,the relationship between thrombus viscosity and shear velocity was evaluated at one hour after the thrombus was collected from the body. The known viscosity model was fitted with experimental data. Results Rheological experiment of thrombus showed that the thrombus carried characteristics of shear-thinning pseudoplastic fluid.The power law equation and Herschel-Bulkley equation were used to fit the thrombus viscosity curve that was changing with the shear velocity. The results indicated that the fitting accuracy of Herschel-Bulkley equation was much higher, based on which the initial yield stress （τ₀） parameter in the equation was evaluated and discussed, and taking τ₀=500 Pa as an indicator the thrombus types were preliminarily classified. Conclusion In a certain sense, this study provides a biomechanical judgment basis for clinical thrombus removal, and it provides a theoretical reference for the study of internal components of thrombus.（J Intervent Radiol, 2020,29: 674-678）更多还原