【摘要】 目的观察阿替普酶联合丹参多酚酸注射液对超早期缺血性卒中患者神经功能缺损的临床疗效。方法选取2017年12月—2019年3月收治的60例超早期缺血性脑卒中患者,随机分为试验组和对照组,对照组患者30例,使用阿替普酶对患者进行治疗;试验组30例,使用阿替普酶联合丹参多酚酸注射液进行治疗,比较两组患者的临床疗效。结果治疗7 d后试验组患者巴氏指数(BI)和美国国立卫生研究院卒中量表(NIHSS)与对照组无明显差异;30 d后试验组BI和NIHSS优于对照组,差异有统计学意义;90 d后试验组BI和NIHSS优于对照组,差异具有统计学意义。结论联合使用阿替普酶和丹参多酚酸注射液能显著改善超早期缺血性脑卒中患者的神经功能缺损。更多还原

【Abstract】 Objective To observe the clinical effect of alteplase combined with danshen polyphenolic acid injection on neurological impairment in patients with ultra-early ischemic stroke. Methods Sixty patients with ultra-early ischemic stroke admitted to from December 2017 to March 2019 were randomly divided into the experimental group and the control group. Thirty patients in the control group were treated with alteplase. In the experimental group,Thirty patients were treated with alteplase combined with danshen polyphenolic acid injection. Results There was no significant difference in BI and NIHSS between the experimental group and the control group 7 days after treatment. ADL and NIHSS in the 30-day experimental group were superior to those in the control group,and the difference was statistically significant. ADL and NIHSS in the 90-day experimental group were superior to the control group,and the difference was statistically significant. Conclusion Combining alteplase with danshen polyphenolic acid injection has a more obvious therapeutic effect and can significantly improve the neurological impairment of patients with ultra-early ischemic stroke.更多还原