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腹腔镜与开放根治性膀胱切除术治疗膀胱癌的疗效对比

Comparison of Laparoscopic and Open Radical Cystectomy in the Treatment of Bladder Cancer

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【作者】 王振单刚储铸钢罗光恒

【Author】 WANG Zhen;SHAN Gang;CHU Zhu-gang;LUO Guang-heng;Department of Urology, Guizhou Provincial People’s Hospital;

【通讯作者】 罗光恒;

【机构】 贵州省人民医院泌尿外科

【摘要】 目的探讨腹腔镜与开放根治性膀胱切除术治疗膀胱癌的疗效。方法方便选取2016年6月—2018年6月该院收治的84例膀胱癌患者作为研究对象,根据手术方式将其分为A组(n=44)和B组(n=40),A组应用腹腔镜根治性膀胱切除术(LRC)治疗;B组应用开放根治性膀胱切除术(ORC)治疗。对两组的术中出血量、手术时间、麻醉止痛药剂量、术后肠道功能恢复时间、住院时间、并发症发生率进行观察比较。结果 A组的手术时间要长于B组(t=21.976,P=0.000);A组的术中出血量、麻醉止痛药剂量、术后肠道功能恢复时间、住院时间均要低于B组,两组间比较差异有统计学意义[(t=19.381、13.567、4.770、12.956;P=0.000,0.000,0.000,0.000)]。A组的并发症发生率(6.82%)要明显低于B组(22.48%),两组比较差异有统计学意义(χ2=4.208,P=0.040)。结论与ORC相比,LRC能明显减少患者的术中出血量、术后麻醉止痛药剂量,缩短患者的术后肠道功能恢复时间和住院时间,且术后并发症较少。

【Abstract】 Objective To investigate the effect of laparoscopy and open radical cystectomy on bladder cancer. Methods Convenient selection a total of 84 bladder cancer patients admitted in our hospital from June 2016 to June 2018 were selected as the research subjects. They were divided into group A(n =44) and group B(n =40) according to the surgical method. Group A Laparoscopic radical cystectomy(LRC) was used for treatment; group B was treated with open radical cystectomy(ORC). The intraoperative blood loss, operation time, anesthetic and analgesic dose, postoperative intestinal function recovery time, hospital stay, and complication rate were compared between the two groups. Results The operation time of group A was longer than that of group B(t=21.976, P=0.000); the intraoperative blood loss, the dosage of anesthetic and analgesics, the postoperative intestinal function recovery time, and the length of hospital stay were lower than those of group B; the comparison between the two groups was statistically significant [(t =19.381, 13.567, 4.770, 12.956;P =0.000,0.000, 0.000, 0.000)]. The incidence of complications in group A(6.82%) was significantly lower than that in group B(22.48%), and the difference between the two groups was statistically significant(χ2=4.208, P=0.040). Conclusion Compared with ORC, LRC can significantly reduce the intraoperative bleeding volume, postoperative anesthetic and analgesic dosage,shorten the postoperative recovery time of intestinal function and hospitalization time, and there are fewer postoperative complications.

【基金】 贵州省人民医院国家自然科学基金培育基金(黔科合平台人才[2018]5764-01)
  • 【文献出处】 中外医疗 ,China & Foreign Medical Treatment , 编辑部邮箱 ,2020年11期
  • 【分类号】R737.14
  • 【下载频次】63
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