【摘要】 目的:观察"三神针"对中风后失眠患者睡眠质量的改善情况及其对血清褪黑素(melatonin,MT)和5-羟色胺(5-hydroxytryptamine,5-HT)的影响。方法:将70例中风后失眠患者随机分为试验组和对照组各35例。对所有患者予以基础治疗及恢复治疗。治疗组采用"三神针"为主进行治疗,对照组采用普通针刺治疗。每天1次,每周治疗5次,每次留针30 min,2周为1个疗程,共治疗2个疗程。对所有病例治疗前后进行匹兹堡睡眠质量指数量表(Pittsburgh sleep quality index,PSQI)、失眠严重指数量表(insomnia severity index,ISI)、汉密尔顿焦虑量表(Hamilton anxiety scale,HAMA)、汉密尔顿抑郁量表(Hamilton depression scale,HAMD)评分及MT、5-HT含量对比,并对治疗过程中遇到的不良事件进行记录。结果:两组PSQI各因子及总分比较,差异有统计学意义(P<0.05);两组ISI评分比较,差异有统计学意义(P<0.05);两组HAMA、HAMD评分比较,差异有统计学意义(P<0.05);试验组有效率97.14%(34/35),对照组有效率82.86%(29/35),两组比较,差异有统计学意义(P<0.05);两组均未出现明显不良反应。结论:"三神针"选穴合理精妙,临床疗效确切,能显著改善中风后失眠患者的PSQI评分、HAMD评分、HAMA评分、ISI评分,改善患者的不适症状,是一种疗效好、痛苦小、易接受的治疗方案。更多还原

【Abstract】 Objective:To observe the improvement of sleep quality of insomnia patients after apoplexy and the influence of "Sanshen acupuncture" and ordinary acupuncture on the level of melatonin(MT) and 5-hydroxytryptamine(5-HT) in the serum of insomnia patients after apoplexy.Methods:70 cases of insomnia after apoplexy were randomly divided into experimental group and control group with 35 cases each.All patients were given basic treatment and recovery treatment.The treatment group was mainly treated with "Sanshen acupuncture",while the control group was treated with ordinary acupuncture,once a day,5 times a week,30 minutes each time,2 weeks as a course of treatment,a total of 2 courses of treatment.Before and after treatment,all patients were assessed with Pittsburgh sleep quality index(PSQI),insomnia severity index(ISI),Hamilton Anxiety Scale(HAMA),Hamilton anxiety scale(HAMA),MT and 5-HT levels were compared,and the efficacy evaluation and adverse events encountered in the course of treatment were recorded.Results:The differences of PSQI factors and total scores between the experimental group and the control group were statistically significant(P<0.05);the difference of ISI between the two groups was statistically significant(P<0.05);there was significant difference in HAMA and HAMD between the two groups(P<0.05);the effective rate of the experimental group was 97.14%,and that of the control group was 82.86%.The difference between the two groups was statistically significant(P<0.05);there was no significant adverse reaction in both groups.Conclusion:The "Sanshen acupuncture" acupoint selection is reasonable and precise,and its clinical effect is accurate.It can significantly improve the PSQI,HAMD,HAMA and ISI score of insomnia patients after stroke,and improve the discomfort symptoms of patients.It is a treatment scheme with good therapeutic effect,little pain,easy acceptance and few side effects.更多还原