【摘要】 目的:优选心痛颗粒的最佳提取工艺。方法:采用L9(34)正交试验法,以乙醇浓度、提取时间、加乙醇量3个因素为提取工艺的影响因素,以阿魏酸含量及干浸膏得率为考察指标,优选心痛颗粒醇提工艺。结果:心痛颗粒最佳提取工艺为用浓度为60%的乙醇回流提取两次,时间分别为2.0、1.5 h,加乙醇量为10倍、8倍。结论:优选的心痛颗粒最佳提取工艺合理可靠,稳定性与重现性好,可为心痛颗粒的制备提供参考。更多还原

【Abstract】 Objective: To optimize the extraction process of Xintong granules. Methods: L9(34) orthogonal test method was used and ethanol concentration, extraction time and the amount of ethanol were the influencing factors of the extraction process. Ferulic acid content and the yield of dry extract were the inspection index to optimize the ethanol extraction process of Xintong granules. Results: The optimal extraction process of Xintong granules was which was extracted twice with 60% ethanol and extraction time was 2.0 h and 1.5 h; and the amount of ethanol added was 10 times and 8 times. Conclusion: The optimal extraction process of the preferred Xintong granules is reasonable and reliable, and the stability and reproducibility are good. It provides a reference for the preparation of Xintong granules.更多还原