【摘要】 目的分析55岁以下的甲状腺乳头状癌(papillary thyroid carcinoma,PTC)患者临床病理特征与预后之间的关系。方法分析山西省肿瘤医院头颈外科190例PTC患者的各临床病理因素和复发率的关系。结果 (1)复发率与诊断时的年龄、肿瘤大小、甲状腺腺外侵犯(extrathyroidal extension,ETE)、多灶、中央区淋巴结转移和颈侧区淋巴结转移有关(P<0.05),但与性别无关(P=0.909);(2)中央区淋巴结转移和侧颈部淋巴结转移是较高复发率的独立危险因素(分别为P=0.023,P=0.001);(3)年龄小于35岁的患者与35～55岁的患者相比,有较高的复发率。结论 55岁以下PTC患者中有颈部淋巴结转移的人更容易复发,年龄小于35岁的患者与35～55岁的患者相比,有更高的复发率。更多还原

【Abstract】 Objective To analyze the relationship between clinicopathological characteristics and prognosis of patients with papillary thyroid carcinoma under 55 years old. Methods Analyzing the relationship between clinical, pathological factors and recurrence rate of 190 PTC patients in Head and Neck Surgery, Shanxi Provincial Cancer Hospital. Results(1)The recurrence rate are related to the age, tumor size, ETE, multifocal, central lymph node metastasis and cervical lateral lymph node metastasis at diagnosis(P<0.05),but are not related to gender(P=0.909).(2) Central node lymph node metastasis and lateral neck lymphnode metastasis are independent risk factors for recurrence rate(P=0.023 and 0.001,respectively).(3)Through comparing patients younger than 35 years old with patients 35～55 years old, there is a higher recurrence rate. Conclusion People with cervical lymph node metastasis among PTC patients under 55 years old are more likely to relapse. Patients younger than 35 years old have a higher recurrence rate than patients 35 to 55 years old.更多还原