【摘要】 目的:探讨慢性阻塞性肺疾病（COPD）伴支气管舒张试验阳性病例的临床特征。方法:收集某院接受治疗的77例COPD患者,所有患者均予以支气管舒张试验,根据试验结果,分为阳性组38例和阴性组39例,比较2组患者一般情况、6 min步行试验（6MWT）、日常生活能力（ADL）评分、用力肺活量（FVC）、呼气峰流速（PEF）、1秒用力呼气量（FEV1）、氧饱和度（SaO₂）、氧分压（PaO₂）、二氧化碳分压（PaCO₂）及血常规等相关结果的差异。结果:2组患者累计一年吸烟量、反复咳嗽及反复咳痰时间比较,差异无统计学意义（P> 0.05）;阳性组6MWT、ADL水平高于阴性组,血红蛋白、嗜酸粒细胞水平低于阴性组,差异均有统计学意义（P <0.05）;阳性组FVC、PEF、FEV₁水平及SaO₂、PaO₂、Pa CO2水平均优于阴性组,差异有统计学意义（P <0.05）。结论:COPD患者中存在部分支气管舒张试验阳性患者,与阴性患者临床特征存在较多相似性,但通过对其进行肺功能水平、血气指标、血常规检查发现,病情程度较阴性组轻,可为临床实施治疗提供依据。更多还原

【Abstract】 Objective: To investigate the clinical features of chronic obstructive pulmonary disease（ COPD） with positive bronchial dilation test. Methods: 77 cases of COPD patients were collected in a hospital,and,after a bronchodilation test,were divided into a positive group（ n = 38） and a negative group（ n = 39） according to the results of the test. The differences of the two groups were compared in terms of conditions in general,exercise endurance,daily life ability（ ADL）,level of pulmonary function,blood gas index,and blood routine,etc. Results: There was no significant difference in the annual amount of smoking,recurrent cough and recurrent sputum production time between the two groups（ P > 0. 05）. The levels of 6 MWT and ADL in the positive group were higher than those in the negative group; the levels of hemoglobin and eosinophils in the positive group were lower than those in the negative group（ all P< 0. 05）. The levels of FVC,PEF and FEV1 as well as the levels of SaO₂,PaO₂ and PaCO₂ in the positive group were all superior to those in the negative group（ all P < 0. 05）. Conclusion: Some COPD patients have positive result in bronchial dilation test. They share many similarities with the negative patients. However,the examination findings of pulmonary function level,blood gas index and blood routine indicate that the disease is less serious than that of the negative group,which can provide basis for clinical treatment.更多还原