【摘要】 目的:探讨妊娠期糖尿病与血清铁、铁蛋白以及转铁蛋白的相关性。方法:选择承德医学院附属医院2018年5月至2020年1月接诊的妊娠中期(孕24周～孕28周)孕妇的资料进行回顾性分析。依据全部孕妇的诊断结果分为GDM组(n=127)和正常组(n=130)。对比两组孕妇的一般临床资料。对比两组孕妇的血液相关指标[血红蛋白(Hb)、平均红细胞体积(MCV)、平均红细胞血红蛋白含量(MCH)、平均红细胞血红蛋白浓度(MCHC)]、血糖指标[空腹血糖、服糖1h血糖、服糖2h血糖]、铁元素相关指标[血清铁(SI)、血清铁蛋白(SF)、血清转铁蛋白(TRF)]。分析铁元素相关指标和空腹血糖的相关性。分析GDM的独立影响因素。结果:GDM组和正常组的性年龄、BMI、孕周的数据差异不具有统计学意义(P>0.05)。GDM组的空腹血糖、服糖1h血糖、服糖2h血糖、SI、SF、TRF均高于正常组(P<0.05)。两组的Hb、MCV、MCH、MCHC数据差异不具有统计学意义(P>0.05)。SI、SF、TRF和空腹血糖之间均呈正相关(P<0.05)。SI、SF、TRF均成为GDM的独立影响因素(P<0.05)。结论:GDM的患者体内容易出现铁储存增多的现象,SI、SF、TRF的增高与GDM发病之间具有一定的关联性,在实际工作中需要加大关注力度。更多还原

【Abstract】 Objective: To explore the relationship between gestational diabetes and serum iron,ferritin and transferrin. Methods: The data of pregnant women in the second trimester of pregnancy( 24 weeks to 28 weeks of pregnancy) who were admitted to the Affiliated Hospital of Chengde Medical College from May 2018 to January 2020 were selected for retrospective analysis. According to the diagnosis results of all pregnant women,they were divided into GDM group( n = 127) and normal group( n = 130). Compare the general clinical data of the two groups of pregnant women. Compare the blood-related indicators [hemoglobin( Hb),mean red blood cell volume( MCV),mean red blood cell hemoglobin content( MCH),mean red blood cell hemoglobin concentration( MCHC) ],blood glucose indicators [fasting blood sugar,blood sugar 1 h blood sugar,serving Sugar 2 h blood glucose],iron-related indicators [serum iron( SI),serum ferritin( SF),serum transferrin( TRF) ]. Analysis of the correlation between iron related indicators and fasting blood glucose was conducted. Analysis of independent factors of GDM was conducted. Results: The data of sex,age,BMI and gestational age in GDM group and normal group were not statistically significant( P >0.05). The fasting blood glucose,blood glucose for 1 h,glucose for 2 h,SI,SF,TRF in the GDM group were higher than those in the normal group( P <0.05). The difference in Hb,MCV,MCH,MCHC data between the two groups was not statistically significant( P >0.05). There was a positive correlation between SI,SF,TRF and fasting blood glucose( P <0.05). SI,SF,TRF have become independent factors of GDM( P < 0.05). Conclusion: Patients with GDM are prone to increased iron storage. The increase in SI,SF,and TRF has a certain correlation with the incidence of GDM. In actual work,more attention is needed.更多还原