【摘要】 目的探讨预见性护理联合丙种球蛋白对ABO溶血新生儿的临床应用效果,以期为ABO溶血新生儿提供科学、合理的综合干预策略。方法选取2018年2月至2019年2月产科出生的ABO溶血新生儿76例,根据采用的护理和治疗方法不同将患者分为研究组39例和对照组37例。对照组采用常规护理和蓝光照射、茵栀黄口服液治疗,研究组采用预见性护理联合丙种球蛋白治疗。统计2组患儿干预前后总胆红素、红细胞压积、红细胞计数,并统计2组患儿住院时间、光疗时间、黄疸消失时间及不良反应发生情况。结果 2组患儿干预后总胆红素水平均较干预前明显下降(P<0.05),研究组干预后总胆红素水平明显低于对照组(P<0.05),2组患儿干预后红细胞压积均较干预前下降(P<0.05),且研究组患儿干预后红细胞压积高于对照组(P<0.05),2组患儿干预后红细胞计数均较干预前下降,对照组干预后与干预前相比差异有统计学意义(P<0.05),且研究组患儿干预后红细胞计数明显高于对照组(P<0.05),研究组患儿住院时间、光疗时间及黄疸消失时间均明显低于对照组(P<0.05),研究组患儿皮肤干燥、皮肤损伤、发热及不良反应总发生率均低于对照组,但差异均无统计学意义(P>0.05)。结论预见性护理联合丙种球蛋白干预策略可以促进ABO溶血新生儿尽快康复,降低不良反应的发生率,具有良好的干预效果。更多还原

【Abstract】 Objective To investigate the clinical application effects of predictive nursing combined with gamma globulin in treatment of ABO hemolysis in neonates,in order to provide a scientific and reasonable comprehensive intervention strategy for treatment of ABO hemolysis in neonates.Methods A total of 76 neonates with ABO hemolysis who were born in our hospital from February 2018 to February 2019 were enrolled in the study,who were divided into research group(n=39) and control group(n=37) according to the different nursing and treatment methods.The patients in control group were treated by routine care and blue light irradiation,and Yinzhihuang oral liquid,howeverr,the patients in research group were treated by predictive nursing combined with gamma globulin.The total bilirubin,hematocrit and red blood cell counts before and after intervention,and the hospitalization time,phototherapy time,disappearance time of jaundice and adverse reactions were observed and compared between the two groups.Results After intervention,the total bilirubin levels in both groups were significantly decreased(P<0.05), moreover,which in research group were significantly lower than those in control group(P<0.05). And the packed red cell volume levels in both groups were significantly lower than those before intervention(P<0.05),which in research group were significantly higher than those in control group(P<0.05). The red blood cell counts in both groups were significantly lower than those before intervention,there were significant differences in red blood cell counts in control group before intervention and after intervention(P<0.05),moreover,which in research group were significantly higher than those in control group(P<0.05). In addition the hospital stay,phototherapy time and jaundice disappearence time in research group were significantly lower than those in control group(P<0.05),and the total incidence rates of dry skin,skin damage,fever and adverse reactions in research group were lower than those in control group,but there were no significant differences between the two groups(P>0.05).Conclusion The predictive nursing combined with gamma globulin intervention strategy can promote the rehabilitation of neonates with ABO hemolysis as soon as possible,which can reduce the incidence of adverse reactions,and has better intervention effects.更多还原