【摘要】 国际上多中心、大型流行病学研究表明,宫内节育器(IUD)的使用与宫颈癌的发生呈一定的负性相关关系。最新的文献阐述了IUD的使用与高危型人乳头瘤状病毒(HR-HPV)感染的获得和持续性无关,对于已有高危型别HPV感染和具有感染风险的女性而言,IUD的使用是安全的。虽然激素类避孕方式与宫颈上皮内瘤变三级(CINⅢ)及宫颈癌的发生率增加有关,但其因果关系一直备受争议,所以关于IUD的长期使用与CINⅡ/Ⅲ级病变之间的潜在关系仍亟待探究。更多还原

【Abstract】 International multi-center and large-scale epidemiological studies have shown that the use of intrauterine contraceptive device(IUD) is negatively correlated with the occurrence of cervical cancer. The latest literature illustrated that the use of IUD has nothing to do with the acquisition and persistence of high-risk human papillomavirus(HR-HPV) infection, and the use of IUD is safe for women with high-risk type HPV infection or with the risk of infection. Although hormonal contraceptive methods are related to cervical intraepithelial neoplasia grade three(CIN Ⅲ) and the increase of the incidence of cervical cancer, the causal relationship has been controversial, so the potential relationship between the long-term use of IUD and CIN Ⅱ/Ⅲ lesions still needs to be explored urgently.更多还原