【摘要】 糖尿病性周围神经病变(DPN)是最常见糖尿病慢性并发症之一,发病较隐匿,通常不被予以重视,晚期甚或造成截肢等严重后果,早期明确诊断、及时干预可显著改善预后,良好的血糖控制是延缓糖尿病慢性并发症发展的基石。研究表明,波动的血糖对机体的损害要高于持续性高血糖状态,本研究旨在综述血糖波动的监测指标、血糖波动在DPN发病机制中的作用,从而为防止DPN的发生和延缓其疾病进程提供新思路。更多还原

【Abstract】 Diabetic peripheral neuropathy(DPN) is one of the commonest chronic complications of diabetes mellitus.With a relatively hidden onset,it usually attracts scanty attention.However,it might lead to severe consequences such as amputation.Early definite diagnosis and timely intervention can significantly improve the prognosis.Good blood glucose control is the cornerstone for delaying the development of chronic complications of diabetes mellitus.Studies have shown that the damage of fluctuating blood glucose to the body is higher than that of persistent hyperglycemia.This study aims to review the monitoring indexes of blood glucose fluctuation and the role of blood glucose fluctuation in the pathogenesis of DPN,so as to provide a new train of thoughts for preventing the occurrence of DPN and delaying the disease progression.更多还原