【摘要】 目的研究北海地区中年人群缺血性脑卒中危险因素综合干预的临床疗效。方法本研究采用整群抽样法纳入2014年10月～2016年10月在本院进行体检的志愿者600例展开研究,按照是否患有缺血性脑卒中进行分组,以187例中年缺血性脑卒中患者作为观察组,以非脑卒中健康体检者413例作为对照组,对两组的临床数据进行分析,总结缺血性脑卒中危险因素,并进行综合干预,分析观察组患者干预前后的临床疗效。结果观察组患者的糖尿病、高血压、高血脂、吸烟、短暂性脑缺血发作、心脏病史、血压、血脂、颈动脉狭窄症、心电图ST-T段改变等比例同对照组进行比较,差异有统计学意义(P <0.05);多元回归分析显示,高血压、高血脂、糖尿病、心脏病史、吸烟、BMI为中年人群缺血性脑卒中的独立危险因素;187例中年缺血性脑卒中患者综合干预后的临床总有效率显著高于干预前,差异有统计学意义(P <0.05)。结论根据北海地区中年人群缺血性脑卒中的危险因素实施综合干预,能够提高临床疗效,为以后预防或降低缺血性脑卒中发病率提供科学依据。更多还原

【Abstract】 Objective To study the clinical efficacy of comprehensive intervention on risk factors of ischemic stroke in middle-aged population in Beihai Region. Methods The cluster sampling method was used to include 600 volunteers who underwent medical examinations in our hospital from October 2014 to October 2016.Patients were grouped according to whether they had ischemic stroke.187 middle-aged ischemic stroke patients were taken as the observation group,and 413 non-stroke healthy people were taken as the control group.The clinical data of the two groups were analyzed,the risk factors of ischemic stroke were summarized,and comprehensive intervention was performed to analyze the clinical efficacy of the observation group before and after intervention. Results The proportions of diabetes,hypertension,hyperlipidemia,smoking,transient ischemic attack, history of heart disease,blood pressure,blood lipids,carotid stenosis and ST-T changes in ECG of the observation group was statistically different from those of the control group(P < 0.05).Multiple regression analysis showed that hypertension,hyperlipidemia,dia betes,history of heart disease,smoking and BMI were independent risk factors for ischemic stroke in the middle-aged population.The total clinical effective rate of 187 middle-aged ischemic stroke patients after comprehensive intervention was significantly higher than that before intervention,and the difference was statistically significant(P < 0.05). Conclusion Implementing comprehensive intervention based on the risk factors of ischemic stroke in middle-aged people in Beihai region can improve clinical efficacy and provide scientific basis for preventing or reducing the incidence of ischemic stroke in the future.更多还原