【摘要】 目的研究抑郁情绪对急性心肌梗死(AMI)患者经皮冠状动脉介入治疗(PCI)术后支架内再狭窄的影响。方法选择本院2017年5月～2020年5月我院收治的92例进行PCI手术的AMI患者作为研究对象,根据患者的抑郁发生情况,分为抑郁组(34例)与非抑郁组(58例)。比较两组患者的汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)、匹兹堡睡眠质量指数(PSQI)、世界卫生组织生活质量测定量表(WHOQOL-BREF)、临床疗效、PCI术后支架内再狭窄率。结果 (1)入组患者中抑郁症发生率为58.6%。抑郁组患者的HAMD和HAMA评分显著高于非抑郁组(P<0.05);(2)抑郁组患者的PSQI评分显著高于非抑郁组,WHOQOL-BREF评分显著低于非抑郁组(P<0.05);(3)抑郁组患者的治疗总有效率(79.41%)显著低于非抑郁组的总有效率(94.83%)(P<0.05);(4)抑郁组患者PCI术后支架内再狭窄率(23.53%)显著高于非抑郁组(5.17%)(P<0.05)。结论 PCI术后患者抑郁发生率较高,导致患者睡眠、生活质量和临床疗效下降,且支架内再狭窄率升高。更多还原

【Abstract】 Objective To study the influence of depression on stent restenosis in patients with acute myocardial infarction(AMI)after after percutaneous coronary intervention(PCI). Methods A total of 92 AMI patients admitted to our hospital from May 2017 to May 2020 underwent PCI were selected as study subjects. According to the incidence of depression,the patients were divided into a depression group(34 cases)and a non-depression group(58 cases). The Hamilton depression scale(HAMD)score,Hamilton anxiety scale(HAMA)score,Pittsburgh sleep quality index(PSQI)score,World Health Organization quality of life measurement scale(WHOQOL-BREF)score,clinical efficacy,and in-stent restenosis rate after PCI between the two groups were compared. Results (1)The incidence of depression in the enrolled patients was 58.6%. HAMD and HAMA scores of depressed patients were significantly higher than those of non-depressed patients(P<0.05).(2)The PSQI score in the depressed group was significantly higher than that in the non-depressed group,and the WHOQOL-BREF score was significantly lower than that in the nondepressed group(P<0.05).(3)The total effective rate in the depression group(79.41%)was significantly lower than that in the non-depression group(94.83%)(P<0.05).(4)The rate of in-stent restenosis after PCI in the depression group(23.53%)was significantly higher than that in the non-depression group(5.17%)(P<0.05). Conclusion The incidence of depression was higher in patients after PCI,leading to a decline in sleep,quality of life and clinical efficacy,as well as an increase in in-stent restenosis.更多还原