【摘要】 子宫内膜癌是妇科三大恶性肿瘤之一,其发病率逐年升高。以手术为主的综合治疗是其主要治疗原则,手术分期是确定子宫内膜癌患者病变范围、评估预后及选择辅助治疗的重要基础。常用的淋巴结分期策略包括系统性淋巴结切除术(LAD)及根据"梅奥标准"行选择性淋巴结切除术(SLAD),但LAD手术风险高,术后并发症多,其治疗意义与生存获益尚存争议。近年来,前哨淋巴结绘图(SLNM)逐渐成为子宫内膜癌手术分期的替代选择,通过切除少量高度相关淋巴结,可提供足够的信息指导手术病理分期及辅助治疗,同时最大程度减少手术损伤而不影响患者预后。综述SLNM在早期子宫内膜癌中的应用进展及相关争议,为临床子宫内膜癌患者手术分期及淋巴结评估的选择提供思路。更多还原

【Abstract】 Endometrial cancer is one of the three main gynecologic malignancies and its incidence is increasing year by year. Surgery-based comprehensive treatment is its main treatment principle, and surgical staging is an important basis for determining the extent of disease, evaluating prognosis, and selecting adjuvant therapy in patients with endometrial cancer.Commonly used lymph node staging strategies include systemic lymphadenectomy(LAD) and selective lymphadenectomy(SLAD) according to the "Mayo criteria". However, LAD has higher surgical risks accompanying many postoperative complications and the survival benefit remains controversial. In recent years, sentinel lymph node mapping(SLNM) has gradually become an alternative to the staging of endometrial cancer. By removing a few highly relevant lymph nodes, it can provide sufficient information to guide surgical pathological staging and adjuvant treatment, while minimizing surgery injury without affecting the patients′ prognosis. This review aims to systematically analyze the progress and related controversies of SLNM in early-stage endometrial cancer, providing evidence for another treatment strategy in surgical staging and lymph node evaluation in endometrial cancer patients.更多还原