【摘要】 目的调查四川成都地区成年人亚临床甲状腺功能减退症(SH)患病率并测定其尿碘水平,探讨成都地区成年人碘营养状态与SH的关系。方法以华西医院2017年53 499例成年体检人群为研究对象,调查四川成都地区成年人SH患病率,并比较不同性别与年龄段患病率;同时分别随机抽取140名SH患者和140名健康对照者,比较两者尿碘水平。结果四川成都地区成年人2017年SH总体患病率为15.7%,其中女性患病率为20.7%,高于男性的12.2%(P<0.001)。同时,随着年龄增长,人群SH患病率逐渐增加(P<0.001);SH患者尿碘水平明显高于健康对照者(P<0.001),以碘超适宜量者和碘过量者为主。结论四川成都地区成年女性SH患病率高于男性,SH患病率随着年龄增加逐渐增多。此外,碘营养过剩与SH有关。更多还原

【Abstract】 Objective To investigate the prevalence and urine iodine level of subclinical hypothyroidism(SH)in adults in Chengdu,Sichuan,and explore the relationship between iodine nutrition status and SH in Chengdu.Methods A survey was conducted on 53 499 adults undergoing physical examination in West China Hospital in 2017.The prevalence of SH in Chengdu,Sichuan was investigated,and the prevalence of SH in different genders and ages was compared.In addition,140 SH patients and 140 healthy controls were randomly selected to compare urine iodine levels.Results The overall prevalence of SH in adults in Chengdu,Sichuan,was 15.7%in 2017.The prevalence of SH in women was 20.7%,which was higher than that in men(12.2%,P<0.001).In addition,the prevalence of SH gradually increased with age(P<0.001).The urinary iodine level of SH patients was significantly higher than that of healthy controls(P<0.001),and patients with SH were mainly those who have an excess of iodine.Conclusion The prevalence of SH in women in Chengdu of Sichuan was higher than that in men,and prevalence of SH increased with age.In addition,iodine excess was related to SH.更多还原