【摘要】 目的观察联合应用前列地尔和金水宝片治疗慢性肾功能不全的效果。方法 80例慢性肾功能不全患者随机采用常规治疗(对照组)或加用前列地尔和金水宝片(治疗组)。比较两者疗效、肾功能、肾血流动力学和血液流变学指标。结果治疗组疗效、双肾内径高于对照组,而肾功能、血液流变学指标和双肾阻力指数低于对照组(P<0.01或0.05)。两组不良反应差异无统计学意义(P>0.05)。结论前列地尔联合金水宝片治疗慢性肾功能不全可提高疗效,改善肾功能。更多还原

【Abstract】 Objective To observe the clinical efficacy of alprostadil and Jinshuibao tablet in chronic renal failure(CRF). Methods Eighty patients with CRF were randomly treated with conventional therapy(control group) or addition of alprostadil and Jinshuibao tablet(observation group). The clinical efficacy, renal function, renal hemodynamics, and hemorheology were compared between two groups. Results Compared with control group, clinical efficacy and birenal inner diameters were higher, while renal function, hemorheology, and birenal resistance indexes were lower in observation group(P<0.01 or 0.05). The adverse reactions were comparable between two groups(P>0.05). Conclusion Combined use of alprostadil and Jinshuibao tablet can improve the clinical efficacy and renal function in patients with CRF.更多还原