【摘要】 目的分析急性冠状动脉综合征(ACS)患者入院血清白蛋白(SA)水平与Syntax评分及住院死亡的关系。方法827例接受冠状动脉造影ACS患者,依据Syntax评分分为低分组(<33分,n=708)和高分组(≥33分,n=119)。通过多元回归分析ACS患者SA水平与Syntax评分及住院死亡的关系。结果与低分组比较,高分组患者的血糖、肌酐、高敏C反应蛋白、肌钙蛋白T峰值均较高,而SA、左心室射血分数(LVEF)、肾小球滤过率(eGFR)则较低,且多支血管病变率、慢性闭塞病变率和住院死亡率亦高于低分组(P<0.05或0.01)。Logistics回归分析显示SA、LVEF和eGFR是Syntax高评分的独立预测因子(P<0.01)。Cox回归分析显示SA(<3.63 mg/dL)是住院死亡的独立预测因子(P<0.01)。结论 ACS患者入院时血清白蛋白水平与Syntax高评分和住院死亡独立相关。更多还原

【Abstract】 Objective To analyze the relationship between serum albumin(SA) level and Syntax score and inpatient mortality in patients with acute coronary syndrome(ACS).Methods A total 827 ACS patients who underwent coronary angiography were divided into the Low Score Group(<33 points,n=708) and High Score Group(≥33 points,n=119).The Multivariate logistic analysis was performed to analyze the relationship between SA and Syntax score or in-hospital mortality.Results Compared with,the High Score Group had the blood glucose,creatinine,hypersensitive C-reactive protein and Troponin T peak higher than the Low Score Group,had the SA,LVEF and eGFR lower than the Low Score Group,and had the rate of multi-vessel disease,rate of chronic occlusive disease and inpatient mortality higher than the Low Score Group(P<0.01 or 0.05).The Cox regression analysis showed that SA(<3.63 mg/dL) is the independent predictor of in-hospital mortality(P<0.01).Conclusion SA is independently related to the high Syntax score and inpatient mortality.更多还原