【摘要】 目的探讨联合检测血清肌钙蛋白Ⅰ(cTnⅠ)、超敏C-反应蛋白(hs-CRP)、D-二聚体(D-D)和尿酸(UA)在老年急性心肌梗死(AMⅠ)早期诊断中的临床应用价值。方法选择某院心内科住院确诊为AMⅠ的92例老年患者为观察组,选取同一时期体检的84例老年健康者为对照组。检测两组血清cTnⅠ、hs-CRP、D-D和UA水平,统计4项指标联合检测对诊断AMⅠ的敏感性和特异性。结果观察组cTnⅠ、hs-CRP、D-D及UA水平均显著高于对照组,差异有统计学意义(P<0.01);4项联合诊断的敏感性(94.6%)、特异性(96.9%)均明显高于各指标的单项检测。结论 cTnⅠ、hs-CRP、DD和UA联合检测可以显著提高老年AMⅠ诊断的敏感性和特异性,对老年AMⅠ的早期诊断具有较高的临床价值。更多还原

【Abstract】 Objective To investigate the combined detection of serum cardiac troponin Ⅰ(cTnⅠ), high-sensitivity Creactive protein(hs-CRP), D-dimer(DD) and uric acid(UA) and their value in early diagnosis of acute myocardial infarction(AMI) in the elderly. Methods 92 elderly patients diagnosed with AMI in the Department of Cardiology of a hospital were selected as the Observation Group and 84 healthy elderly volunteers receiving physical examination during the same period were selected as the Control Group. The blood serum cTnⅠ, hs-CRP, DD and UA level of the two groups were detected. The AMI sensitivity and specificity of the combined detection of the four markers was statistically analyzed. Results The Observation Group had the cTnⅠ, hs-CRP, DD and UA level significantly higher than the Control Group, and the differences were statistically significant(P<0.01). The sensitivity(94.6%) and specificity(96.9%) of the combined detection of the four markers were significantly higher than the single detection of each marker. Conclusion The combined detection of cTnⅠ, hs-CRP, D-D and UA can significantly improve the sensitivity and specificity of AMI diagnosis in the elderly and has a high clinical value in the early diagnosis of AMI in the elderly.更多还原