【摘要】 目的探讨红细胞分布宽度(RDW)和血小板分布宽度(PDW)的变化在急性心肌梗死(AMI)治疗效果中的作用。方法选取2014年10月至2018年9月合肥市第三人民医院收治的110例急性心肌梗患者,根据治疗效果分为有效组和无效组。检测治疗前后的RDW和PDW,并计算红细胞分布宽度变化值(RDW-C)、血小板分度宽度变化值(PDW-C),以及红细胞分布宽度变化率(RDW-Cr)、血小板分布宽度变化率(PDW-Cr)。结果有效组较无效组的RDW、PDW变化值(-1.01±3.25 vs 1.62±2.12,-1.10±4.5 vs 0.25±1.2)及变化率(-2.15±6.2 vs 3.10±6.8,-6.3±9.3 vs 1.45±7.1)显著提高(P<0.01)。多因素Logistic回归分析显示RDW-C(OR=1.012,95%CI:1.015～1.121)、PDW-C(OR=1.011,95%CI:1.019～1.082)是疗效的独立预测因素(P<0.01)。ROC曲线分析显示,RDW和PDW的变化值及变化率在评价治疗效果方面差异均有统计学意义(P<0.05)。结论 RDW与PDW治疗前后变化值及变化率可用于急性心肌梗死治疗效果的评价。更多还原

【Abstract】 ObjectiveTo investigate the role of erythrocyte distribution width(RDW)and platelet distribution width(PDW)in the treatment of acute myocardial infarction(AMI).Methods110 cases of acute myocardial infarction in Hefei ThirdPeople’s Hospital from October 2014 to September 2018 were selected and divided into effective group and ineffective group accordingto treatment effect. RDW and PDW were measured before and after treatment. The change values and rates of RDW and PDW were cal-culated[change values of erythrocyte distribution width(RDW-C),change values of platelet index width(PDW-C),change rates oferythrocyte distribution width(RDW-Cr),change rates of platelet distribution width(PDW-Cr)].ResultsThe changes of RDW inthe effective group(-1.01±3.25 vs 1.62±2.12)and PDW in the effective group(-1.10±4.5 vs 0.25±1.2),RDW rates(-2.15±6.2 vs 3.10±6.8)and PDW rates(-6.3±9.3 vs 1.45±7.1)were statistically significant(P<0.01). Multivariate logistic regression analysis found that RDW-C(OR=1.012,95%CI:1.015-1.121)and PDW-C(OR=1.011,95%CI:1.019-1.082)were independent predictors of efficacy(P<0.01). ROC curve analysis showed that the changes and rates of RDW and PDW were significantly different in evaluating the therapeutic effect(P<0.05).Conclusionthe changes of RDW and PDW before and after treat-ment can be used to evaluate the therapeutic effect of acute myocardial infarction.更多还原