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糖尿病患者血管动脉硬化与脉搏波传导速度的相关性分析

Analysis of correlation between vascular atherosclerosis and pulse wave velocity in diabetic patients

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【作者】 罗建平曾祥辉王祥贵许祖芳肖春庆刘恺

【Author】 Luo Jianping;Zeng Xianghui;Wang Xianggui;Xu Zufang;Xiao Chunqing;Liu Kai;Department of Cardiology, Ganzhou People’ s Hospital;Department of Cardiology, Ganzhou Municipal Hospital;

【通讯作者】 曾祥辉;

【机构】 赣州市人民医院心内科赣州市立医院心内科

【摘要】 目的探讨脉搏波传导速度在糖尿病动脉硬化中的临床应用价值。方法选择2014年1月至2018年1月在本院住院的糖尿病患者366例作为研究对象,均行颈动脉彩色多普勒超声检测以及测定R波脉搏波传导速度(PWV),根据颈动脉是否形成粥样硬化斑块,将其分为动脉粥样硬化组与正常组,比较两组患者PWV。结果糖尿病患者中,硬化组276例,正常组90例,动脉硬化组心电R波脉搏传导速度明显快于正常组,差异具有统计学意义(P<0.05);动脉硬化组与正常组性别、年龄比较差异无统计学意义,糖尿病患者,动脉硬化发生率明显升高,糖化血红蛋白越高,PWV越快。结论 PWV对于糖尿病患者动脉粥样硬化的诊断具有重要应用价值,糖尿病组动脉硬化发病率明显升高,PWV能准确评估外周血管动脉硬化程度,值得临床推广。

【Abstract】 Objective To investigate the clinical application value of pulse wave velocity in diabetic arteriosclerosis. Methods 366 patients with diabetes mellitus hospitalized in our hospital from January 2014 to January 2018 were selected as the study subjects. Carotid artery color Doppler ultrasonography and R-wave pulse wave conduction velocity(PWV) were measured. According to whether carotid artery formed atherosclerotic plaques,they were divided into atherosclerotic group and normal group. The difference of PWV between the two groups was compared. Results Among the patients with diabetes mellitus, 276 were in the sclerosis group, 90 cases in the normal group, the ECG R wave pulse conduction velocity in the atherosclerosis group was significantly faster than that in the normal group, the difference was statistically significant(P<0.05); there was no significant difference between the atherosclerosis group and the normal group in gender and age. The incidence of atherosclerosis significantly increased in diabetic patients. The higher the glycosylated hemoglobin, the faster the PWV. Conclusion PWV is of great value in the diagnosis of atherosclerosis in diabetic patients. The incidence of atherosclerosis in diabetic patients is significantly increased. PWV can accurately assess the degree of peripheral arteriosclerosis, and it is worthy of clinical promotion.

【基金】 江西省重点研发计划项目(20161BBG70027)
  • 【文献出处】 当代医学 ,Contemporary Medicine , 编辑部邮箱 ,2020年05期
  • 【分类号】R587.2
  • 【被引频次】2
  • 【下载频次】106
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