【摘要】 目的:探讨慢性心力衰竭（CHF）与低钙血症的相关性。方法:搜集2017年2月～2019年3月因CHF入住我院的患者,分析比较不同心功能分级患者血清Ca²⁺水平、低钙血症发生率及血清Ca²⁺水平与血肌酐、血尿酸、N末端B型利钠肽前体（NT-pro BNP）、左心室射血分数（LVEF）、左心室舒张末期内径（LVEDD）的相关性。结果:心功能Ⅱ级组血清Ca²⁺水平（2.14±0.17mmol/L）明显高于Ⅲ级组（2.08±0.15mmol/L）及Ⅳ级组（2.03±0.14mmol/L）,差异均有统计学意义（均P<0.01）;心功能Ⅱ级组（58.82%）低钙血症发生率明显低于Ⅲ级组（79.75%）和Ⅳ级组（86.96%）,差异均有统计学意义（均P<0.01）。与正常血钙组相比,低钙血症组血肌酐、血尿酸、NT-pro BNP和LVEDD升高,而LVEF降低,差异均有统计学意义（均P<0.01）。血清Ca²⁺水平与血肌酐、血尿酸、NT-pro BNP、LVEDD呈负相关,与LVEF呈正相关（均P<0.01）。结论:CHF患者血清Ca²⁺水平与心功能级别相关,可作为患者预后的预测因子。更多还原

【Abstract】 Objective:To investigate the correlation between chronic heart failure（CHF）and hypocalcemia.Methods:Patients admitted to our hospital due to CHF from February 2017 to March 2019 were collected.The serum Ca²⁺level and the incidence of hypocalcemia in patients with different grades of cardiac function were analyzed and compared.The correlation between serum Ca²⁺level and serum creatinine,blood uric acid,N-terminal pro-B-type natriuretic peptide（NT-pro BNP）,left ventricular ejection fraction（LVEF）,left ventricular end diastolic diameter（LVEDD）were analyzed.Results:The serum Ca²⁺levels of patients with cardiac function grade II（2.14±0.17 mmol/L）was significantly higher than that of grade Ⅲ（2.08±0.15 mmol/L）and grade IV（2.03±0.14 mmol/L）（both P <0.01）.The incidence of hypocalcemia in cardiac function grade II（58.82%）was significantly lower than that of grade Ⅲ（79.75%）and grade IV（86.96%）,with statistically significant difference（both P<0.01）.The serum creatinine,serum uric acid,NT-pro BNP and LVEDD were increased in the hypocalcemia group compared with the normal group,while the LVEF was decreased（all P<0.01）.The serum Ca²⁺level was negatively correlated with serum creatinine,serum uric acid,NT-pro BNP and LVEDD,while positively correlated with LVEF（all P<0.01）.Conclusion:The level of serum Ca²⁺in CHF patients is related to the grade of cardiac function,which can be used as a predictor for CHF prognosis.更多还原