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分娩镇痛过程中地塞米松对硬膜外持续性给药产妇发热的疗效研究

Study on the effect of dexamethasone on the fever of the parturient in the process of labor analgesia

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【作者】 陈美霞邵冰心陈治君吴思航

【Author】 Chen Meixia;Shao Bingxin;Chen Zhijun;Wu Sihang;Women’s and children’s health care center,Xinhui District,Jiangmen City,Guangdong Province;

【机构】 广东省江门市新会区妇幼保健院

【摘要】 目的:探讨在分娩镇痛过程中硬膜外给予地塞米松对产妇发热的影响。方法:将2018年5月—2019年5月在我院接受硬膜外分娩的100例产妇作为研究对象,采取随机分组的方式,分为常规组与实验组,每组50例。常规组采取罗哌卡因+舒芬太尼+氯化钠常规性治疗方案,实验组在常规性治疗方案的基础上,增加地塞米松。对比两组在分娩过程中体温变化、不良反应以及新生儿生命体征。结果:实验组分娩时,镇痛发生后的3 h、4 h以及5 h、胎儿娩出时、分娩后第1小时、2小时体温明显低于常规组(P<0.05);实验组在研究过程中,出现发热等不良反应的几率低于常规组;两组新生儿基础生命体征的差异无统计学意义。结论:新的治疗方案,产妇发生发热、寒战的几率较低,且不增加新生儿风险。

【Abstract】 Objective:To investigate the effect of epidural dexamethasone on intrapartum fever during labor analgesia.Methods:During the study,100 epidural parturients who delivered in our hospital from 2018 to 2019 were randomly divided into two groups:the conventional group and the experimental group,with 50 patients in each group.The conventional group was treated with ropivacaine + sufentanil +sodium chloride,while the experimental group was treated with dexamethasone.Temperature changes,adverse reactions and newborn vital signs during labor were compared between the two groups.Results:In the experimental group,after labor analgesia at 3 h,4 h and 5 h,and the temperature of the fetus at delivery,1 h and 2 h after delivery was significantly lower than that in the normal group(P<0.05).The incidence of fever and other adverse reactions in the experimental group was lower than that in the conventional group.There was no significant difference in basic vital signs between the two groups.Conclusion:In the new treatment,the incidence of fever and chills in puerpera is lower,and the risk of newborn is not increased.

【基金】 广东省江门市卫生计生局科研立项项目(18A119)
  • 【文献出处】 北方药学 ,Journal of North Pharmacy , 编辑部邮箱 ,2020年06期
  • 【分类号】R614
  • 【被引频次】3
  • 【下载频次】70
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