【摘要】 目的:分析中药治疗骨质疏松症的用药规律。方法:以"关键词=骨质疏松症AND任意字段=中药"为检索式,应用计算机检索中国知网、维普网和万方数据3大中文数据库2007年1月1日至2017年12月31日收录的关于中药治疗骨质疏松症的文献。通过阅读文献题名、摘要、全文,按照文献的纳入和排除标准对文献进行筛选,提取文献中涉及的中药,分析用药规律。结果:初检共检索出文献1112篇,经过筛选后共纳入文献490篇,涉及中药125味。125味中药中出现频率(记录有该味药的文献数/纳入文献总数×100%)≥25%的有13味,按照出现频次排序由高至低依次为熟地黄(254次)、淫羊藿(250次)、杜仲(237次)、鹿茸(195次)、黄芪(190次)、牛膝(188次)、骨碎补(185次)、补骨脂(173次)、山萸肉(164次)、山药(160次)、茯苓(154次)、丹参(150次)、白术(145次)。13味中药涉及的药性包括温(1793次)、平(502次)、寒(150次),涉及的药味包括甘(1335次)、苦(841次)、咸(195次)、辛(173次)、酸(164次)、涩(164次)、淡(154次),脏腑归经主要归肾(2150次)、肝(1813次)、脾(822次)、肺(504次)、心(304次)经,主要功效包括补肾(1546次)、补脾(649次)、补肝(589次)、补气(444次)及活血化瘀(338次)等。结论:用于治疗骨质疏松症的常用中药依次为熟地黄、淫羊藿、杜仲、鹿茸、黄芪、牛膝、骨碎补、补骨脂、山萸肉、山药、茯苓、丹参、白术等,涉及的药性依次为温、平、寒,涉及的药味依次为甘、苦、咸、辛、酸、涩、淡,脏腑归经依次为归肾、肝、脾、肺、心经,药物主要功效依次为补肾、补脾、补肝、补气及活血化瘀等。更多还原

【Abstract】 Objective: To analyze the medication rule of Traditional Chinese Medicine( TCM) for treatment of osteoporosis( OP).Methods: OP( keyword) and TCM( any field) were used as index terms to retrieve all the articles about TCM for treatment of OP included from January 1,2007 to December 31,2017 from China national knowledge internet,Vip Database and Wanfang Database through computer. The articles were screened through reading titles,abstracts and full texts according to the inclusion and exclusion criteria of the articles,and the TCMs involved in the articles were searched out,and their medication rules were analyzed. Results: One thousand one hundred and twelve articles were searched out. After screening,490 articles were included in the final analysis,including 125 TCMs. In the 125 TCMs,the occurrence frequency( ratio of the number of articles in which the TCMs were recorded to the number of all included articles) of 13 TCMs were ≥ 25%. According to high-to-low occurrence frequency,the 13 TCMs included radix rehmanniae praeparata( 254 times),epimedium( 250 times),eucommia ulmoides( 237 times),cornu cervi pantotrichum( 195 times),astragalus membranaceus( 190 times),achyranthes bidentata( 188 times),drynaria fortunei( 185 times),fructus psoraleae( 173 times),pulp of cornus( 164 times),rhizoma dioscoreae( 160 times),poria cocos( 154 times),salvia miltiorrhiza( 150 times) and atractylodes macrocephala koidz( 145 times). For the 13 TCMs,the drug properties included warm( 1793 times),normal( 502 times) and cold( 150 times); the drug flavours included sweet( 1335 times),bitter( 841 times),salty( 195 times),pungent( 173 times),sour( 164 times),astringency( 164 times) and bland( 154 times); the Zang-Fu( viscera) meridian distributions presented mainly with kidney meridian( 2150 times),liver meridian( 1813 times),spleen meridian( 822 times),lung meridian( 504 times) and heart meridiam( 304 times); and the clinical effects presented mainly with tonifying kidney( 1546 times),tonifying spleen( 649 times),tonifying liver( 589 times),tonifying qi( 444 times) and activating blood and resolving stasis( 338 times). Conclusion: The common TCMs which are used for treatment of OP include radix rehmanniae praeparata,epimedium,eucommia ulmoides,cornu cervi pantotrichum,astragalus membranaceus,achyranthes bidentata,drynaria fortunei,fructus psoraleae,pulp of cornus,rhizoma dioscoreae,poria cocos,salvia miltiorrhiza and atractylodes macrocephala koidz in turn. Their drug properties present with warm,normal and cold in turn; their drug flavours present with sweet,bitter,salty,pungent,sour,astringency and bland in turn; their Zang-Fu( viscera) meridian distributions include kidney meridian,liver meridian,spleen meridian,lung meridian and heart meridiam in turn; and their clinical effects present mainly with tonifying kidney,tonifying spleen,tonifying liver,tonifying qi and activating blood and resolving stasis in turn.更多还原