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基于文献回顾分析动物骨髓炎模型制备方法的特点研究

Research Progress on Establishment Method of Animal Osteomyelitis Model Based on Literature Review

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【作者】 李鼎鹏谢兴文汪付田乔莉徐世红李宁

【Author】 Li Dingpeng;Xie Xingwen;Wang Futian;Qiao li;Xu Shihong;Li Ning;Gansu provincial institute of Traditional Chinese Medicine;Gansu provincial hospital of Traditional Chinese Medicine;

【通讯作者】 谢兴文;

【机构】 甘肃省中医药研究院甘肃省中医院

【摘要】 目的:通过参考文献总结造模方法,以此改进达到快速、有效、经典的兔骨髓炎模型制备方法。方法:以"骨髓炎模型"、"骨髓炎动物模型"为关键词在知网、万方、维普等数据库进行检索,并对详细描述建立骨髓炎模型并成功的文献进行筛选,对符合标准的文献分析总结。结果:筛选后得出了符合标准的22篇中文文献和12篇外文文献,分析后总结为6类模型制备方法。结论:通过与人体相近的骨髓炎动物模型探索,可以制备出方法简便、成功率高、时间短、成本低的理想模型。

【Abstract】 Objective: By summarizing the modeling method based on literature review, to establish a fast, effective and classic method of rabbit osteomyelitis model. Methods: The key words such as "osteomyelitis model" and "animal model of osteomyelitis" were selected to search in databases of HowNet, Wanfang, Weipu, etc. The documents describing the establishment of osteomyelitis models were successfully screened and analyzed.Results: After screening, 22 Chinese literatures and 12 foreign literatures were obtained, which were analyzed and classified into 6 types of model establishment methods.Conclusion: By exploring animal models of osteomyelitis similar to the human, an ideal model with simple method, high success rate, short time, and low cost may be prepared.

【基金】 国家自然科学基金项目(81460735);兰州市人才创新创业项目(NO.2015-RC-23);甘肃省中医药管理局科研课题(NO.GZK-2015-29);甘肃省科技计划资助(No.18JR2TA016);甘肃省中医院院级课题(No.院2017-4)
  • 【文献出处】 中药药理与临床 ,Pharmacology and Clinics of Chinese Materia Medica , 编辑部邮箱 ,2019年05期
  • 【分类号】R681.2;R-332
  • 【被引频次】4
  • 【下载频次】174
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