【摘要】 目的:观察纳入的老年恶性腔积液患者经复方苦参注射液联合顺铂胸腔灌注治疗的临床疗效分析。方法:选择2015年8月-2017年12月的恶性胸腔积液患者共40例,将40例患者随机分为对照组和观察组各20例,对照组采用复方苦参注射液单药胸腔灌注治疗。观察组采用复方苦参注射液联合顺铂胸腔灌注治疗。观察两组患者的临床疗效,以《中药新药临床研究指导原则》(2002版)制定中医证候疗效改善率、VEGF含量。结果:观察组的治疗总有效率为80.00%,高于对照组的50.00%(P <0.05);观察组的治疗临床症状改善率为95.00%,高于对照组的70.00%(P <0.05),对比差异具有统计学意义。结论:复方苦参注射液联合顺铂胸腔灌注治疗老年恶性胸腔积液的临床疗效较高,能有效改善中医临床症状及体征。更多还原

【Abstract】 Objective: To observe clinical efficacy of the Fufang Kushen injection( 复方苦参注射液) plus cisplatinum intrapleural infusion on geriatric malignant pleural effusion. Methods: 40 cases were divided into two groups, 20 cases in each. The control group was given the Fufang Kushen injection; and the observation group was given cisplatinum intrapleural infusion more. Results: The total efficiency was 80.00% in the observation group, higher than 50.00% in the control group, P<0.05. The clinical symptom improvement rate was 95.00% in the observation group, higher than 70.00% in the control group(P<0.05). Conclusion: The Fufang Kushen injection plus cisplatinum intrapleural infusion on geriatric malignant pleural effusion show a good effect.更多还原